Phthalate Risks and Alternatives | Center for Advanced Life
In one study , phthalates such as BBP, DBP, DEHP, and DiBP were administered to rats to see the effects of exposure. The results showed that testosterone production decreased with 20% of the top dose, and when 40% of the top dose was administered, researchers noticed significant changes in maternal body weight gain, total resorptions, and fetal
3 Identified alternatives to DEHP, DBP and BBP
3 Identified alternatives to DEHP, DBP and BBP 3.1 Functional mode of external plasticisers 3.2 Introduction to plasticiser substance families 3.3 Alternative plasticisers and polymers used in toys and childcare articles 3.3.1 Toys and childcare articles on the Danish Market 3.3.2 Toys and childcare articles on the Dutch market
Phthalates - ECHA - Europa
Phthalates Phthalates Phthalates form a family of synthetic chemicals with a wide variety of uses, ranging from consumer to industrial products. There are different kind of phthalates and they are commonly used as softeners to make plastics, such as PVC, more flexible and durable.
Alternatives to phthalates to medical devices
The use of phthalates, particularly DEHP, BBP, DBP and DIBP, in consumer products with known human exposure, has been a focus point the last decades due to their reproductive and endocrine disrupting effects evidenced on certain animals.
Guidance for Industry - Food and Drug Administration
The European Commission identified DBP, DEHP, and BBP as reproductive toxicants (Directive 2005/84/EC), and the European Union prohibits their use as ingredients in cosmetics (Directive 2005
- What is a substitute for DBP?
- Has very similar application properties to DBP and may therefore be used to substitute for DBP in most, if not all, of its applications. The main alternatives to DEHP have been the two phthalates di-isononyl phthalate (DINP) and di-isodecyl phthalate (DIDP).
- What are alternatives to DEHP?
- The main alternatives to DEHP have been the two phthalates di-isononyl phthalate (DINP) and di-isodecyl phthalate (DIDP). As illustrated in Figure 2.3 in Sweden the shift from DEHP to first of all DINP took mainly place in the period 1999 to 2002.
- Can EU manufacturers use DBP & DBP in articles?
- Currently, EU manufacturers could use DEHP, DBP, DIBP, and BBP in articles within the scope of the restriction proposal if they apply for an authorisation, while importers are not required to apply (as authorisation requirements do not apply to imported articles).
- When can a product containing DEHP & DBP be placed on the market?
- Articles containing DEHP, DBP, DIBP, and BBP in a concentration, individually or in combination, greater than or equal to 0.1% by weight of the plasticised material shall not be placed on the market. Paragraph 1 shall apply three years from the entry into force of the restriction.
- Can flexible PVC be used as a substitute for DEHP?
- Substances with identified significant environment and health effects (CMR or PBT, based on reviews in COWI, 2009 a) were not suggested for further assessment. Besides the direct alternatives to DEHP, DBP and BBP used as chemicals in various applications, a large number of materials can substitute for flexible PVC in the production of the products.
- What is Diisobutyl phthalate (DIBP)?
- Diisobutyl phthalate (DIBP) is a specialist plasticiser often used in combination with other high molecular weight phthalates. It is a fast fusing plasticiser which by itself it is too volatile for PVC applications. It is frequently used as a gelling aid in combination with other plasticisers.
