Direct and transgenerational effects of low doses
Di- (2-ethylhexyl) phthalate (DEHP) is an endocrine disrupting chemical commonly used as a plasticizer in medical equipment, food packaging, flooring, and children's toys. DEHP exposure during early development has been associated with adverse neurobehavioral outcomes in children.
IJMS | Free Full-Text | Transgenerational Effects of Di(2
Di (2-ethylhexyl) phthalate (DEHP) is widely used as a plasticizer in the manufacture of polyvinylchloride plastics and has been associated with concerns regarding male reproductive toxicity.
Prenatal exposure to an environmentally relevant phthalate
Exposure to di (2-ethylhexyl) phthalate and diisononyl phthalate during adulthood disrupts hormones and ovarian folliculogenesis throughout the prime reproductive life of the mouse Toxicol. Appl. Pharmacol. (2025) D.D. Meling et al. The effects of a phthalate metabolite mixture on antral follicle growth and sex steroid synthesis in mice Toxicol.
Transgenerational effects of the plasticizer di-2-ethylhexyl
In this study, we conducted a chronic toxicity assessment of di-2-ethylhexyl phthalate (DEHP) on the life history traits of Daphnia magna across three generations. In the first generation, the
Exposure to the plasticizer, Di-(2-ethylhexyl) phthalate
Exposure to the plasticizer, Di- (2-ethylhexyl) phthalate during juvenile period exacerbates autism-like behavior in adult BTBR T + tf/J mice due to DNA hypomethylation and enhanced inflammation in brain and systemic immune cells - ScienceDirect Abstract Section snippets References (68) Progress in Neuro-Psychopharmacology and Biological Psychiatry
