Dibutyl Phthalate Pharmaceutical Secondary Standard
Dibutyl Phthalate [CAS No. 84-74-2] is a phthalate ester used as a plasticizer, available as a pharmaceutical secondary standard and certified reference material for pharmaceutical analysis and quality control testing. Buy from Sigma-Aldrich.
Dibutyl phthalate 99 84-74-2
Dibutyl phthalate (DBP) is most commonly used as a plasticizer in a variety of household products. It has the ability to leach and evaporate into the environment while using or disposing of these products. [ 1] [ 2] Therefore, studies are being conducted to assess its toxic and apoptotic effects. [ 1]
DATA ON MANUFACTURE, IMPORT, EXPORT, USES AND
port uses and releases of three phthalates: benzyl butyl phthalate (BBP), dibutyl phthalate (DBP), and bis(2-ethylhexyl) phthalate (DEHP), as well as information on potential alternatives to these phthalates. This report concerns DBP. The data collection for the three substances has been undertaken under the Specific
Guideline on the use of phthalates as excipients in human
Dibutyl phthalate (DBP) DBP was associated with an anti-androgenic effect in a human cell line as it inhibited the binding of dihydrotestosterone to the androgen receptor with an IC 50 of 74 M (Christen et al. 2010). DBP was devoid of oestrogenic activity in vitro (Lee et al. 2012).
Phthalates - Safe Cosmetics
Phthalates share a similar chemical structure and are widely used in consumer products. Two are widely used in personal care products: 1) dibutyl phthalate (DBP) is used in nail polish, and is listed by the EU as an endocrine-disrupting compound of high concern. [3] Some companies have phased DBP out of nail products.
