Phthalate and novel plasticizer concentrations in food items
The toxicity information for replacement plasticizers is limited to a few animal studies, thus, the human health implications of chronic exposures to replacement plasticizers are poorly understood
A review of common non-ortho-phthalate plasticizers for use in food
Available assessments from US CPSC, EFSA, other governmental and non-governmental organizations, and published toxicology studies were used to show that these plasticizers are generally well-studied and demonstrate low toxicity with a focus on potential carcinogenicity, reproductive, developmental, and endocrine related adverse effects as well as biodegradation, aquatic toxicity, and
A review of common non-ortho-phthalate plasticizers for use in food
Food contact substance approvals and toxicology studies. Plasticizers reviewed in this paper were selected from non-ortho-phthalate plasticizers reported in a study by FDA staff (Carlos et al., 2018), from the relevant information in the List of Available Datasets from the U.S. Food and Drug Administration (FDA, 2025a), and from European Food
Alternative Plasticizers As Emerging Global Environmental and Health
It has been estimated that the global plasticizer market is expected to grow from 13967.9 million dollars in 2018 to 16700.6 million dollars in 2024,75thereby indicating the potential magnitude of this emerging environmental problem.
An update on the hazard of and exposure to diethyl hexyl phthalate
Taking all data on migration and toxicity in consideration, 1,2-cyclohexanedicarboxylic acid, diisononylester (DINCH), and tris (2-ethylhexyl)benzene-1,2,4-tricarboxylate display a more favorable profile compared to DEHP. For these promising alternatives, a risk assessment for use in medical devices should be conducted.
- What phthalates are toxic?
- Other phthalates, including, but not limited to, di-n-propyl phthalate, diisobutyl phthalate, di-n-pentyl phthalate, dicyclohexyl phthalate, and di(2-propylheptyl) phthalate may also contribute to the cumulative health risks of phthalates. The purpose of this report is to provide a brief overview of the toxicity of the o-DAP’s.
- Do phthalates from recycled plastics affect human health?
- We found no reviews of epidemiological human studies on the impact of phthalates from recycled plastics on human health. We recommend that future research should use urine samples as exposure measures, consider confounders in analyses and measure impacts on female reproductive systems.
- Are phthalates safe?
- Health impacts of phthalates associated with exposures below current European Regulatory Levels deemed safe (indicated by the blue vertical line). Graphic produced using data from Maffini et al., 2019, Maffini et al., 2021, a review of 41 epidemiological studies which associated increased risk for human health effects with levels of phthalates.
- Are phthalates a risk factor for human health?
- Graphic produced using data from Maffini et al., 2019, Maffini et al., 2021, a review of 41 epidemiological studies which associated increased risk for human health effects with levels of phthalates. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
- Does phthalate toxicity affect microbial diversity?
- In recent years, many metagenomic profiles of phthalate-enriched soil have been constructed to analyze the effect of phthalate toxicity on soil enzymes and microbial diversity (Cheng et al., 2018; Ma et al., 2019). Several reports disclosed the gradual abolishment of microbial communities due to PAE contaminations along with the
- Which company produces DEHT plasticizer?
- DEHT plasticizer is produced by the Eastman Kodak Company, under the name Eastman 168 Plasticizer. It is important to note that while DEHT contains the word 'phthalate' in its name, it is not a phthalate ester, which is a different class of compounds.
