Exploiting Polymeric Films as a Multipurpose Drug Delivery
Polymeric films are drug delivery systems that maintain contact with the delivery tissue and sustain a controlled release of therapeutic molecules. These systems allow a longer time of drug contact with the target site in the case of topical treatments and allow the controlled administration of drugs. They can be manufactured by various methods such as solvent casting, hot melt extrusion
Topical Polymeric Films and Transdermal Patches | BASF Pharma
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TEC Plasticization of Topical Polymeric Films | SpringerLink
The incorporation of plasticizers into polymer films increases their flexibility [4] and permits the mechanical properties to be matched to those of skin. In this way, film breakage is avoided and the area across which drug transport occurs remains constant.
Solid Dispersion Product Families | BASF Pharma
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Film-Forming Systems in Topically Administered
Polymeric films can be previously prepared or formed in situ, after application of a film-forming system (FFS) used as a drug dosage form or to protect a dosage form or as a drug dosage form...
- How can plasticizers be used to make polymers soft and flexible?
- By adding plasticizers to compatible polymers, the materials can be modified in such a way that they become soft and flexible by decreasing their glass transition temperature. Plasticizers are classified according to their molecular structure into monomeric or polymeric types.
- Why are plasticizers important in biopolymer-based films & coatings production?
- In biopolymer-based films and coatings production, plasticizers are also essential additives since they can improve flexibility and handling of films, maintain integrity and avoid pores and cracks in the polymeric matrix .
- What are the benefits of topical polymeric films & transdermal patches?
- Due to their benefits such as physical barrier formation, ease of application, and reduced dosing frequency, topical polymeric films and transdermal patches are often associated with improved patient compliance.
- Which polymers are plasticized?
- The plasticizers produced have been applied in 60 polymers and more than 30 groups of products. Industrially, the most common plasticized polymers are PVC, poly (vinyl butyral) (PVB), poly (vinyl acetate) (PVAc), acrylics, cellulose molding compounds, nylon, polyamides and certain copolyamides.
- How are plasticizers classified?
- Plasticizers are classified according to their molecular structure into monomeric or polymeric types. The choice of the plasticizer is dependent on the requirements that have to be met for the final product and the conditions around that product’s use.
- What types of plasticizers are used in hydrophilic polymers?
- In addition to water, the most commonly used plasticizers are polyols, mono-, di- and oligosaccharides. Polyols have been found to be particularly effective for use in plasticized hydrophilic polymers .
