Pharmaceutical Tablet Film Coatings | PharmaCentral
A pharmaceutical film coating is a polymer-based membrane applied onto solid dosage forms, such as tablets, capsules and granules, in order to impart certain desired attributes that are otherwise absent in the uncoated product.
Effects of plasticizers and surfactants on the film forming
Uniformity in tablet weight gain and thickness of the film coat data obtained from cast film measurements are supportive for elegant film formation. The quality of aqueous film coat or the plasticizer efficiency in case of PEG-400 is in the order 1.5 > 0.5 > 1.0% and for PG 1 > 4 > 3%. This preliminary study infers that plasticizer
Effects of plasticizers and surfactants on the film forming
DOI: 10.1016/j.jsps.2009.08.004 Corpus ID: 45438680; Effects of plasticizers and surfactants on the film forming properties of hydroxypropyl methylcellulose for the coating of diclofenac sodium tablets.
Effects of plasticizers and surfactants on the film forming
The quality of the aqueous film coats or the plasticizer efficiency in case of PEG-400 is in the order 1.5 > 0.5 > 1.0% and for PG 1 > 4 > 3% which can be stated on the basis of less incidence...
Plasticizer Excipients | American Pharmaceutical Review
Plasticizer Excipients Plasticizers are used mainly for oral solid dosage forms. Plasticizers are added to the polymers used as film forming agents in order to make the polymer pliable and soft, enhancing the flexibility and plasticity of the films.
- What is film coated tablet?
- Development of film coated tablet has based on different types of polymer in various organic solvent system, aqueous system or hydro alcoholic system to prepare pharmaceutical solid dosage form. Film coating are dry blend of polymer, plasticizer and surfactants. A polymer used for film coating of tablets has great importance.
- What plasticizers are used in film coating?
- This reaction results in increased film flexibility and reduced residual stresses within the coating as it shrinks around the core during drying. Examples of plasticizers commonly used in film coating processes include: Polyols, such as glycerol (glycerin), polyethylene glycols (PEG 200 – 6000 grades) and propylene glycol.
- Which film forming formulation is best for tablet coating?
- 4. Executive summary In conclusion, tablet coating films made of HPMC 5cPs with the addition of PEG at 1.5% and SLS at 0.3% and films made of HPMC 5cPs with PG at 1% and Tween-80 at 0.3% could be considered as an elegant film forming formulation for solving different coating problems generally faced in an industrial scale.
- How do plasticizers affect film coating?
- Film coating is a complex process that involves different factors. To ensure spreading and/or film forming capability plasticizers are added. The type and concentration of plasticizers can affect the film properties, as revealed by several investigations ( Mortada, 1990, Siepmann et al., 2005, James, 1997 ).
- Why are plasticizers important in film forming?
- Plasticizers are a very important component of the film-forming formulation. They are to be added in a minute amount in the formulation to provide the necessary flexibility to the film and to enhance the water permeation through the film.31Some plasticizers also act as drug diffusion enhancers along with providing plasticity to the film.
- What are plasticizers used for?
- Plasticizers are relatively low molecular weight materials which are added to film-coating formulations to modify the physical properties of polymers.
