Pharmaceutically Used Plasticizers - IntechOpen
Recent Advances in Plasticizers 46 2. Pharmaceutically used plasticizers The primary role of all plasticizers as low molecular weight non-volatile additives is to improve the flexibility and processability of polymers by lowering the second order transition temperature (glass transition temperature, Tg) (Rosen, 1993). The extent of Tg
Pharmaceutically Used Plasticizers | IntechOpen
Pharmaceutically Used Plasticizers Written By Eva Snejdrova and Milan Dittrich Submitted: November 11th, 2011 Published: March 21st, 2012 DOI: 10.5772/39190 IntechOpen From the Edited Volume Recent Advances in Plasticizers Edited by Mohammad Luqman Book Details Order Print Chapter metrics overview 26,853 Chapter Downloads View Full Metrics
[PDF] Pharmaceutically Used Plasticizers | Semantic Scholar
Although there are many plasticizers used in the chemical industry, only a few of them have been approved for pharmaceutical applications. The natural-based plasticizers characterized by low toxicity and low migration are required nowadays not only for pharmaceutical and medical… View via Publisher intechopen.com Save to Library Create Alert Cite
PHARMACEUTICALLY USED PLASTICIZERS: A REVIEW
an overview of the important types of plasticizers which exist, and gives details of properties of the plasticizers. The choice of an appropriate plasticizer requires a wide background of information.
Recent Advances in Plasticizers | IntechOpen
Pharmaceutically Used Plasticizers By Eva Snejdrova and Milan Dittrich 26,851 22 4. Pharmaceutical Applications of Plasticized Polymers By Eva Snejdrova and Milan Dittrich 12,619 10 5. Plasticizers in Transdermal Drug Delivery Systems By Sevgi Güngr, M. Sedef Erdal and Yldz zsoy 8,387 8 6.
- Is hydrophilic polymer an internal plasticizer of polymeric drug delivery systems?
- As well structural water in the hydrophilic polymer seems to be an internal plasticizer of the polymeric drug delivery systems. In case of contact with body fluids after application the hydrophilic plasticizer can be released from polymer and thus conditions for the incorporated drug release are changed.
- Are plasticizers suitable for pharmaceutical applications?
- The extensive use of polymers in medical and pharmaceutical applications including particularly packaging, medical devices, drug carriers and coatings has caused a substantial demand for the proper plasticizers. Although there are many plasticizers used in the chemical industry, only a few of them have been approved for pharmaceutical applications.
- What are the different types of plasticizers used in polymers?
- Oily, waxy,or fatty substances were applied as plasticizers. Other i nvention polymer matrix. poly- DL -lactide- co-glycolide (PLGA) were produced. plasticizer, PEG, was added to the polymers. It was degradation-controlled phase. The plasticizer accelerated polymer. The plasticizer dep ressed the burst effect for controlled phase.
- Why are water-insoluble plasticizers used in polymer dispersions?
- ecially when water-insoluble plasticizers are used. Water insoluble plasticizers have to be emulsif ed in the aqueous phase of the polymer dispersions. During plasticization of the polymer dispersions, the plasticizer partitions into the colloidal polymer particles and softens them thus promoting particle
- Are polymeric drug delivery systems plasticizers?
- Plasticizer as minor component of polymeric drug delivery systems has not been strictly defined. Even liquid drugs or liquids with a potential pharmacodynamic effect can serve as plasticizers. As well structural water in the hydrophilic polymer seems to be an internal plasticizer of the polymeric drug delivery systems.
- Are natural-based plasticizers suitable for pharmaceutical and medical applications?
- The natural-based plasticizers characterized by low toxicity and low migration are required nowadays not only for pharmaceutical and medical applications. In this respect, most of traditional plasticizers are not applicable in this area.
