Effects of plasticizers and surfactants on the film forming
The plasticizing efficiency is measured by the lowering of the incidence of coat defects. In this study two plasticizers namely polyethylene glycol 400 (PEG-400) and propylene glycol (PG) were selected.
Film coating | SEPPIC
Seppic develops effective and easy-to-use film coating agents for medications and dietary supplements, thanks to its expertise in film coating, and in selecting compositions based on a tablet’s type and desired functionality. The tablet coating process The coating process results in the formation of a thin layer of polymer around the tablet.
An Easy-to-Use Tablet Coating Polymer to Increase Coating
Screened plasticizers included various polyethylene glycols PEGs, polyols triethyl citrate, triacetin, glycerol, Parteck SI 150 sorbitol, and Parteck M 200 mannitol. Screening was conducted by forming coating solutions from stock Parteck COAT excipient and plasticizer solutions.
Pharmaceutical Tablet Film Coatings | PharmaCentral
The polymer is the film former and the main component on the formulation. The ideal polymer is one capable of producing smooth, thin films that are reproducible under routine coating conditions. The range of materials that can be used as film formers is very wide and covers materials that may be natural, synthetic or semi-synthetic.
Film Formers & Plasticizers for Tablet | Pullulan Applications
Pullulan has excellent binding strength and film forming properties, which makes it suited for tablets and granules. It is also used as an additive for solid oral dosage forms (Ex: Binder, Tablet coating, Granulation? Ingredient (s): Pullulan Dosage Form: Tablet Category: Film Formers & Plasticizers Route of Administration (Grade): Oral
- Which film forming formulation is best for tablet coating?
- 4. Executive summary In conclusion, tablet coating films made of HPMC 5cPs with the addition of PEG at 1.5% and SLS at 0.3% and films made of HPMC 5cPs with PG at 1% and Tween-80 at 0.3% could be considered as an elegant film forming formulation for solving different coating problems generally faced in an industrial scale.
- What is tablet film coating?
- Tablet film coating is a technology-driven process, and the evolution of coated dosage forms depends on advancements in coating technology, equipment, analytical techniques, and coating materials. In film coating processes, the intra- and inter-batch coating uniformity of tablets is critical to ensure the quality of the final product.
- Which plasticizers are used in aqueous based film coating formulation?
- Proper optimization for the aqueous based film coating formulation was undertaken primarily employing plasticizers like polyethylene glycol (PEG) 400 and propylene glycol (PG).
- What are plasticizers used for?
- Plasticizers are also used to reduce the glass transition temperature (Tg) and increase flexibility to avoid cracking and subsequent peel-off of polymer films . Many coating techniques have been developed for solvent-based or solvent free processes to improve the efficiency of the coating process.
- How do plasticizers affect film properties?
- The type and concentration of plasticizers can affect the film properties, as revealed by several investigations ( Mortada, 1990, Siepmann et al., 2005, James, 1997 ). The plasticizing efficiency is measured by the lowering of the incidence of coat defects.
- How to optimize tablet film coating process?
- Modeling approaches are also actively pursued to predict the influence of operation parameters on the quality of final products and optimize the process variables of tablet film coating . The concerted efforts of experiments and computational modeling can save time and cost to optimize the tablet coating process.
