Extraction of the Plasticizers Diethylhexylphthalate and Pol
The plasticizer used almost exclusively in medical polyvinylchloride (PVC) products to keep them flexible is the phthalate derivative diethylhexylphthalate (DEHP). In tubing systems, it can make up as much as 40% of the tubing by weight. Because this plasticizer is not bound to the PVC molecules, it can migrate into the surrounding media.
Extraction of the plasticizers diethylhexylphthalate and
The amount of plasticizer extracted was compared between groups and days. Results: In the feeding solution group, the extraction of DEHP ranged from 200 to 542 microg after 1 week and from 660 to 1700 microg after 4 weeks. The extraction of polyadipate was 10 times lower than that of DEHP.
Analytical methods for the determination of DEHP plasticizer
Until 2010, diethylhexylphthalate (DEHP) was the plasticizer most commonly used to soften PVC medical devices (MDs), because of a good efficiency/cost ratio. In flexible plasticized PVC, phthalates are not chemically bound to PVC and they are released into the environment and thus may come into contact with patients.
Extraction, Identification and Determination of di-(2
The present study describes extraction, identification of phthalate plasticizer using infrared spectrometry, proton and C13 spectrometry and determination of phthalate plasticizer in the blood samples bags that are used in Erbil city hospitals depending upon its complexation with Fe2+ and Cr3+ions present in the blood.
Torsten Hannmann's research works | Universitt Heidelberg
Extraction of the Plasticizers Diethylhexylphthalate and Polyadipate From Polyvinylchloride Nasogastric Tubes Through Gastric Juice and Feeding Solution Citing article Feb 2007 PubMed Ulrike...
- How are plasticizers extracted?
- In their study, plasticizers were extracted by dissolving PVC samples in THF and precipitating with ethanol . The extraction yields of plasticizers (from 91 to 120%) were similar to results presented in our paper (from 91 to 104%), but with greater variability.
- Can plasticizers be extracted from PVC tubing?
- Hence, the extraction yields (% w/w of PVC sample) from PVC tubing were 96.9 ± 2.5%, 103.7 ± 0.5%, 94.0 ± 1.6%, 90.6 ± 1.8% and 99.7 ± 0.5% for ATBC, DEHP, DEHT, DINCH and TOTM, respectively ( Table 5 ). Based on these results, this extraction technique seems to be adapted to the extraction of these plasticizers from PVC tubing. Table 5.
- How are plasticizers extracted from PVC-tubing?
- Plasticizers were extracted from PVC-tubing by dissolving PVC in THF then precipitating it in methanol with a yield of over 90% for each plasticizer. This assay could feasibly be used to quantify plasticizers in PVC medical devices. 1. Introduction
- How phthalate plasticizers are synthesized?
- Phthalate plasticizers such as DEHP are synthesized from phthalic acid, in which the two carbonyl groups are in ortho-position to one another, i.e., on neighboring carbon atoms in the aromatic ring (Fig. 1). Phthalic acid is esterified with various alcohols, but most commonly with 2-ethyl hexanol, to form liquid DEHP (Fig. 1).
- What are the limits of quantification of PVC plasticizers?
- The reported limits of quantification were 5 μg/mL and 25 ng/mL, respectively. After extraction from PVC tubes by diluting with THF and precipitating PVC with ethanol, the plasticizers were quantified by GC–MS with high sensitivity (LOD between 0.06 and 0.25 μg/mL and LOQ between 0.01 and 2.0 μg/mL, depending on the plasticizer).
- Which plasticizers were separated by Gradient elution?
- Five plasticizers, acetyl tributyl citrate, di- (2-ethylhexyl)-phthalate, di- (ethylhexyl)-terephthalate, di-isononyl-1,2-cyclohexane-dicarboxylate, and trioctyl trimellitate, were separated on a C8 stationary phase (2.6 μm, 100 mm × 4.6 mm) under gradient elution in 13 min.
