Acetyl Tributyl Citrate, the Most Widely Used Phthalate
Akira Takeshita, Junko Igarashi-Migitaka, Kazusa Nishiyama, Hideyo Takahashi, Yasuhiro Takeuchi, Noriyuki Koibuchi, Acetyl Tributyl Citrate, the Most Widely Used Phthalate Substitute Plasticizer, Induces Cytochrome P450 3A through Steroid and Xenobiotic Receptor, Toxicological Sciences, Volume 123, Issue 2, October 2011, Pages 460–470, https
Acetyl tributyl citrate, the most widely used phthalate
In particular, acetyl tributyl citrate (ATBC), an industrial plasticizer widely used in products such as food wrap, vinyl toys, and pharmaceutical excipients, strongly activated human and rat SXR. ATBC increased CYP3A4 messenger RNA (mRNA) levels and enzyme activity in the human intestinal cells but not in human liver cells.
Acetyltributylcitrate
Acetyltributylcitrate is an organic compound that is used as a plasticizer. As such, it is a potential replacement of DEHP and DINP. [1] It is a colorless liquid that is soluble in organic solvents. It is found in nail polish and other cosmetics. It is prepared by acetylation of tributylcitrate.
Characterizing the obesogenic and fatty liver-inducing
Acetyl tributyl citrate (ATBC) is a non-phthalate plasticizer widely used in food packaging, personal care products, medical devices and children’s toys etc. Due to its high leakage rate from plastics, exposure risk of ATBC keeps increasing.
Preparation and evaluation of acetylated mixture of citrate
Tributyl citrate (TBC) and acetyl tributyl citrate (ATBC), as phthalate alternative plasticizers, show limited application due to low migration resistance, high volatilization rate and intense
