Analysis of the impact of three phthalates on the freshwater

                                               
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Guideline on the use of phthalates as excipients in human

                                               
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Hazards of diethyl phthalate (DEP) exposure: A systematic

                                               
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Diethyl phthalate 99.5 84-66-2 - Sigma-Aldrich

                                               
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Biomonitoring Summary | CDC

                                               
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  • What temperature is diethyl phthalate (DEP)?
  • Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ?
  • ) Diethyl phthalate (DEP) is a phthalate ester. It is a colourless liquid without significant odour but with a bitter disagreeable taste.
  • What is diethylphthalate used for?
  • Diethylphthalate is used as solvent and vehicle for fragrance and cosmetic ingredients, as well as alcohol denaturant. DEP was reported in 1995 as an ingredient in 67 formulations in the USA at concentrations ranging from less than 0.1% to 50%.
  • What does diethyl phthalate taste like?
  • It is a colourless liquid without significant odour but with a bitter disagreeable taste. Diethyl phthalate is produced by the reaction of ethanol with phthalic anhydride, in the presence of a strong acid catalyst: It finds some use as a specialist plasticiser in PVC, it has also been used as a blender and fixative in perfume.
  • Is diethyl phthalate a potent developmental toxicant?
  • DEP is not a potent developmental toxicant, although skeletal variations and decreased growth were observed. Low dose studies reported large magnitudes of effect but significant concerns for bias were identified. Diethyl phthalate (DEP) is widely used in many commercially available products including plastics and personal care products.
  • Why is diethyl phthalate a worst case?
  • Because of the wide spread use of Diethyl phthalate, the SCCNFP made a worst case calculation. These data have to be compared to the results published in 2001 (Ref.115), referring to a paper mentioning a survey on more than 2000 perfumes compounds intended for hydro-alcoholic cosmetics, and reported a 97.5 percentile of use for DEP of 28.6%.
  • Is diethylphthalate soluble in water?
  • Solubility Water: fairly soluble, 1.08 g/l Miscible in all quantities in alcohol, ether, acetone, hydrocarbons, aliphatic solvents and vegetable oils. 2.2. Diethylphthalate is used as solvent and vehicle for fragrance and cosmetic ingredients, as well as alcohol denaturant.