Di-isononyl Phthalate (DINP); Final Scope of the Risk
Di-isononyl Phthalate (DINP) (1,2-Benzene- dicarboxylic acid, 1,2-diisononyl ester); Manufacturer Request for Risk Evaluation Under the Toxic Substances Control Act (TSCA); Notice of Availability and Request for Comments. Federal Register. ( 84 FR 42912, August 19, 2025) (FRL-9998-25). 2. EPA.
Evonik committed to general-purpose plasticizer DINP
Evonik is committed to offering customers the general-purpose plasticizer DINP (diisononyl phthalate) on a global basis. The safe and long-lasting use of plasticizers is always Evonik's top priority. Recently, Evonik joined with other manufacturers in the High Phthalates Panel (HPP), a sector group of the American Chemistry Council (ACC), in a
Development of a physiologically based pharmacokinetic model
ABSTRACT. A physiologically based pharmacokinetic (PBPK) model for di-isononyl phthalate (DiNP) was developed by adapting the existing models for di(2-ethylhexyl) phthalate (DEHP) and di-butylphthalate (DBP).
Phthalates Action Plan1 I. - US EPA
These plasticizers can cover a broad range of phthalate applications, such as adhesive, sealants, inks, floor coverings, wall paper, and medical disposables. It is worth noting that isosorbide esters could be prepared under solvent-free conditions (Chalecki, 1997), providing an environmentally friendly approach to manufacturing.
EPA Releases Proposed Rule Requiring TRI Reporting on DINP
DINP is a common chemical name for a family of di-ester phthalates widely used as plasticizers. These chemicals are colorless, oily liquids with high boiling points, low volatilities, and are poorly soluble in water. The treatment of plastics with DINP-category chemicals provides greater flexibility and softness to the final product.
- What is diisononyl phthalate (DINP)?
- Policies and ethics Diisononyl phthalate (DINP) is one of the widely used dialkyl phthalate (DAPs) softeners in the production of flexible polyvinyl chloride (PVC) plastics, copolymers, and resins. These phthalate plasticizers are incorporated into the PVC polymer matrix to impart...
- Does diisononyl phthalate cause transgenerational reproductive effects?
- Nikiforov AJ, Keller LH, Harris SB (1996) Lack of transgenerational reproductive effects following treatment with diisononyl phthalate (DINP). Toxicologist 30:119. NIOSH (1982) Information profiles on potential occupational hazards: phthalates. NIOSH-00188272. Syracuse Research Corp, Syracuse, NY. NTP (2000) Di-isononyl phthalate.
- Is diisononyl phthalate a hazard?
- Babich MA (1998) Preliminary hazard assessment of diisononyl phthalate (DINP) in children’s products. U.S. Consumer Product Safety Commission, Washington, DC. Babich MA, Chen S-B, Greene MA (1998) The risk of chronic toxicity associated with exposure to diisononyl phthalate (DINP) in children’s products.
- How is Di-isononyl phthalate produced?
- Di-isononyl phthalate is produced by one-step ester-ification of phthalic anhydride with isononanol (INA) and a catalyst. Two types of isononanol can be used for the synthesis: either a pure C9 fraction (synthe-sized from isooctene), or a C8-C10 fraction, C9-rich (synthesized from C7-C9, C8-rich alkene).
- Which phthalate esters are used in the eco-profile?
- In the current Eco-profile, only one plasticiser was used, whereas in the previous eco-profile three high volume commodity phthalate esters including Di-2-ethylhexyl phthalate (DEHP) and Di-isodecyl phthalate (DIDP) as well as DINP were considered. In addition further changes were made (data sources, system, method-ology).
- Is diethylhexyl phthalate estrogenic?
- IPCS (1992) Diethylhexyl phthalate. Environmental Health Criteria 131. International Programme on Chemical Safety, World Health Organization, Geneva, Switzerland. Jobling S, Reynolds T, White R, Parker MG, Sumpter JP (1995) A variety of environmentally persistent chemicals, including some phthalate plasticizers, are weekly estrogenic.
