Sorbitol Function | Film Formers & Plasticizers
A natural inert polymer and ready-to-use coating system for fast aqueous film coating saves up to 50% or more time. Ingredient (s): Hydroxypropyl Pea Starch, Sorbitol, Titanium Dioxide, Stearic Acid Dosage Form: Capsule, Tablet Category: Film Formers & Plasticizers Route of Administration (Grade): Not Available
Pharmaceutical Tablet Film Coatings | PharmaCentral
The polymer is the film former and the main component on the formulation. The ideal polymer is one capable of producing smooth, thin films that are reproducible under routine coating conditions. The range of materials that can be used as film formers is very wide and covers materials that may be natural, synthetic or semi-synthetic.
Plasticizer Excipients - CD Formulation
Plasticizer can increase the plasticity of the film-forming material, and make the formed film soft, tough, and not easily broken. Broadly speaking, any substance that can make the polymer soft and elastic can be called a plasticizer. Plasticizers are a class of substances with smaller molecules.
Propylene Glycol | Film Formers Plasticizers | Solutions by
Applications: Liquid plasticizer with high ADI, hydrophilic solvent & humectant in emulsions, skin penetration enhancer in topical formulaitons. Ingredient (s): Propylene Glycol Dosage Form: Capsule, Tablet Category: Film Formers & Plasticizers Route of Administration (Grade): Not Available Pharmacopoeia Reference: Ph. Eur., JP, FCC, USP
Thin-film drug delivery
Pullulan has been the most widely used film former (used in Listerine PocketPak, Benadryl, etc.) Plasticizers [ edit] Plasticizer is a vital ingredient of the OS formulation. It helps to improve the flexibility and reduces the brittleness of the strip.
- Which polymers are used in a plasticizer?
- The polymers are; PVP: polyvinylpyrrolidone (K10), MCC: microcrystalline cellulose (Avicel PH-101) and HPMC: hydroxypropyl-methylcellulose (E19). The chosen plasticizer is PEG400: polyethylene glycol 400. All the compounds are purchased from Sigma–Aldrich.
- Is Peg a good plasticizer for HPMC and PvP?
- We predict the miscibility of the blends. The methods show similar results. PEG is a good plasticizer for HPMC and PVP. During the formulation of solid dosage forms coating, plasticizers are added to the film forming polymer to improve the mechanical properties of the coating shell of the drug product.
- How does polymer-plasticizer incompatibility affect drug release?
- Polymer-plasticizer incompatibility influences not only the mechanical properties but also drug release , . Permanence of a plasticizer means its tendency to remain in the plasticized material; i.e. long term compatibility. It depends on the size of the molecule and on its rate of diffusion.
- Do plasticizers affect polymeric coating properties?
- Various studies have been reported in the literature, investigating the effect of plasticizers on the properties of the final polymeric coating. Laboulfie et al. studied the effect of plasticizer on the mechanical resistance and thermal behavior of composite coating films.
- Which plasticizer is used to make polyvinylpyrrolidone?
- The chosen plasticizer is PEG400: polyethylene glycol 400. All the compounds are purchased from Sigma–Aldrich. Polyvinylpyrrolidone or povidone (PVP) occurs as a fine, white to creamy-white colored, described as a synthetic polymer consisting essentially of linear 1-vinyl-2-pyrrolidinone groups .
- Why do polymers need a plasticizer?
- For polymers with limited film-formation ability, a plasticizer may be added to ease the deformation and to favor colloidal particles coalescence. The plasticizer partially eliminates the interactions responsible for the mechanical cohesion between the chains, and therefore increases their mobility.
