PHTHTE_J - Centers for Disease Control and Prevention
Phthalates and Plasticizers Metabolites Laboratory Procedure Manual (August 2025) Laboratory Quality Assurance and Monitoring Urine specimens are processed, stored, and shipped to the Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA for analysis.
NHANES 2011-2012: Phthalates & Plasticizers Metabolites
Refer to the 2011-2012 Laboratory Data Overview for general information on NHANES laboratory data. Subsample Weights Urinary phthalates and plasticizers metabolites were measured in a one third subsample of persons 6 years and older. Special sample weights are required to analyze these data properly.
Phthalates Factsheet | National Biomonitoring Program | CDC
CDC scientists measured 13 phthalate metabolites in the urine of 2,636 or more people aged 6 years and older who took part in the National Health and Nutrition Examination Survey (NHANES) during 2003–2004. CDC published these findings in the Fourth National Report on Human Exposure to Environmental Chemicals.
NHANES - Whats New Archive - CDC
Urinary Phthalates and Plasticizers Metabolites (PHTHTE_G 2011-2012) Urinary Polyaromatic Hydrocarbons (PAH_G 2011-2012) Urinary Total Arsenic and Speciated Arsenics (UAS_G 2011-2012) Urine Heavy Metals (UHM_G 2011-2012) Volatile Organic Compounds and Metabolites in Urine (UVOC_G 2011-2012) September 2014 Publications
[PDF] Changing Trends in Phthalate Exposures: Zota and
In fact, for the most recent NHANES survey (2011–2012), scientists at the Centers for Disease Control and Prevention are beginning to release population-level data for the urinary metabolite of
- Where are phthalate metabolites found?
- Sci. Technol. 2011, 45, 7, 3138–3144 The occurrence of 14 phthalate metabolites was found in human urine samples collected from seven Asian countries: China, India, Japan, Korea, Kuwait, Malaysia, and Vietnam. Phthalate metabolites were found in all samples, indicating widespread exposure of humans to phthalates in these Asian countries.
- How many phthalate metabolites are found in human urine?
- The occurrence of 14 phthalate metabolites was found in human urine samples collected from seven Asian countries: China, India, Japan, Korea, Kuwait, Malaysia, and Vietnam. Phthalate metabolites we...
- How phthalates are metabolized?
- Phthalates can be rapidly metabolized to their respective primary monoesters and further to oxidized metabolites in human body (Guo et al., 2011b). In detail, normally metabolic pathway of phthalates involves two steps: in the first phase, phthalates are metabolized to monoesters by esterase and lipase in intestines or other tissues.
- Which countries have the highest phthalate metabolite concentrations?
- The highest total (the sum of 14 phthalates) phthalate metabolite concentrations were found in samples collected from Kuwait (median: 1050 ng/mL), followed in decreasing order by samples from India (389 ng/mL), China (234 ng/mL), Vietnam (133 ng/mL), Japan (120 ng/mL), Korea (117 ng/mL), and Malaysia (94.9 ng/mL).
- How do phthalate metabolites differ from parent phthalates?
- Metabolites display different toxic mechanism compared to parent phthalates. Differences exist in distribution of phthalate metabolites in multiple human specimens. Urinary profiles of phthalates vary markedly for people on different continents. Reasonable FUE data are suggested for phthalate exposure assessment by human experiments.
- Do human monitoring studies provide baseline levels of phthalate exposure?
- Human monitoring studies performed in Asia, America and Europe have provided the population exposure baseline levels for typical phthalates in different regions. Urine is the preferred matrix than other specimens for phthalate exposure study.
