Substances and methods used in doping | Reuters

                                               
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WADA publishes 2025 Prohibited List | World Anti Doping Agency

                                               
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World Anti-Doping Agency (WADA) Prohibited List | USADA

                                               
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Synthetic Peptides in Doping Control: A Powerful Tool for an

                                               
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Banned Performance Enhancing Substances & Methods - Drug Use

                                               
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  • Can analytical chemistry detect doping in athletes?
  • Advances in analytical chemistry are a requisite for the majority of significant anti-doping research fields, hence numerous such analytical based experimental approaches or techniques, like mass spectrometry, gas chromatography, etc., are routinely employed to detect doping in athletes.
  • What are the principles of doping analysis?
  • The principles of existing doping analysis can be summarized as follows: (1) Detection methods: Doping control laboratories use a variety of analytical techniques to detect banned substances in athletes’ samples, including mass spectrometry (MS), gas chromatography (GC), and liquid chromatography (LC).
  • Can synthetic peptides be used in doping?
  • The detection and/or quantification of synthetic peptides used in doping poses an additional analytical challenge due to factors such as emergence of new peptides, very short lifetimes, and low concentrations in the body, and they can mimic naturally produced molecules, trigger biological processes indirectly, etc.
  • Why are peptides attractive for doping?
  • Peptides are very diverse molecules that can participate in a wide variety of biological processes. In this way, peptides are attractive for doping, since these molecules can activate or trigger biological processes that can improve the sports performance of athletes.
  • Why is peptide analysis important in doping control?
  • Along with current trends in pharmaceutical industry the analysis of proteins and peptides remains an important issue in doping control. Sophisticated analytical tools are still mandatory to improve their distinction from endogenous analogs.
  • What is chemical doping?
  • Chemical doping involves exposing a polymer such as melanin, typically a thin film, to an oxidant such as iodine or bromine. Alternatively, the polymer can be exposed to a reductant; this method is far less common, and typically involves alkali metals.