Dibutyl phthalate - n-Butyl phthalate, DBP - Sigma-Aldrich
C6H4-1,2-[CO2(CH2)3CH3]2. Synonyms: n -Butyl phthalate, DBP, Phthalic acid dibutyl ester, Dibutyl phthalate. CAS 84-74-2. Molecular Weight 278.34. Browse Dibutyl
Dibutyl phthalate
Dibutyl phthalate ( DBP) is an organic compound which is commonly used as a plasticizer because of its low toxicity and wide liquid range. With the chemical formula C 6 H 4 (CO 2 C 4 H 9) 2, it is a colorless oil, although commercial samples are often yellow. [3] Production and use [ edit]
Guidance for Industry - Food and Drug Administration
exposure to dibutyl phthalate (DBP) and di(2-ethylhexyl) phthalate (DEHP). In particular, the guidance recommends that you, as part of the pharmaceutical industry, avoid the use of these two
Di-n-butyl Phthalate (DBP) - Proposition 65 Warnings Website
Di-n-butyl Phthalate (DBP) Why am I being warned about potential exposure to DBP? DBP is on the Proposition 65 list because it can cause birth defects or other reproductive harm. Exposure to DBP during pregnancy may affect development of the child, and may also harm the male and female reproductive systems.
Guideline on the use of phthalates as excipients in human
Dibutyl phthalate (DBP) DBP was associated with an anti-androgenic effect in a human cell line as it inhibited the binding of dihydrotestosterone to the androgen receptor with an IC 50 of 74 M (Christen et al. 2010). DBP was devoid of oestrogenic activity in vitro (Lee et al. 2012).
