Risk assessment of endocrine disrupting phthalates and
Risk assessment and hormone evaluation were carried out for di(2-ethylhexyl) phthalate (DEHP) and dibutyl phthalate (DBP), endocrine disrupting chemicals (EDCs), in 302 Korean children (n = 223) and adolescents (n = 79) (< age 19). Urinary and serum concentrations of DEHP, MEHP (mono(2-ethylhexyl
Registration Dossier - ECHA - Europa
Registration Dossier. ... Dibutyl phthalate EC Number: 201-557-4 EC Name: Dibutyl phthalate CAS Number: ... DBP DNBP Dibutyl phthalate
Registration Dossier - ECHA - Europa
For Dibutyl phthalate, a default factor of 4 for allometric scaling from rat to human was used for dermal NOAEL.. AF for other interspecies differences: 2.5 Justification: Factor 2.5 is a default factor for interspecies differences remaining after application of allometric scaling (where applicable). AF for intraspecies differences: 5
South Korea Proposes to Strengthen Phthalates Under its
Section 3.1.3 ‘Phthalate Plasticizer’ MOTIE Notice 2025-052 of January 25, 2025 to amend Common Safety Standards for Children’s Products: Common Safety Standards for Children’s Products: Scope: Children’s products: Children’s products: Phthalate* BBP, DBP, DEHP, DIDP, DINP, DnOP and DIBP: BBP, DBP, DEHP, DIDP, DINP and DnOP
Risk assessment of endocrine disrupting phthalates and
Risk assessment and hormone evaluation were carried out for di(2-ethylhexyl) phthalate (DEHP) and dibutyl phthalate (DBP), endocrine disrupting chemicals (EDCs), in 302 Korean children (n = 223) and adolescents (n = 79) (< age 19).
- Is dibutyl phthlate a toxic phthalate?
- Dibutyl phthlate ester was the most toxic of the phthalates tested. The toxic order of 3 of the esters was dibutyl phthalate greater than diethyl phthalate greater than dimethyl phthalate. For more Ecotoxicity Excerpts (Complete) data for DIBUTYL PHTHALATE (28 total), please visit the HSDB record page. The substance is toxic to aquatic organisms.
- Can dibutyl phthalate be quantified?
- Dibutyl phthalate was identified, not quantified, in a sample of lichen (Hypogymnia physodes) and moss (Hylocomium splendens) collected from Minnesund, Norway the summer of 1979 (1).
- What is the KOC value of dibutyl phthalate?
- A mean sediment log Koc value of 3.8 was calculated from the mean dibutyl phthalate concentration in water and suspended particulate matter from Lake Yssel, The Netherlands (6). The Henry's Law constant for dibutyl phthalate is reported as 1.81X10-6 atm-cu m/mole (1).
- How long does dibutyl phthalate hydrolysis last?
- Hydrolysis half-lives of 3.4 years and 125 days at pH values of 7 and 8, respectively, have been estimated for dibutyl phthalate. Occupational exposure to dibutyl phthalate may occur through inhalation of dust or vapors and dermal contact with this compound at workplaces where dibutyl phthalate is produced or used.
- How is di-n-butyl phthalate metabolized?
- Metabolism of di-n-butyl phthalate proceeds mainly by nonspecific esterases in the gastrointestinal tract, which hydrolyze of one butyl ester bond to yield mono-n-butyl phthalate, the primary toxic metabolite. Mono-n-butyl phthalate is conjugated with glucuronic acid via glucuronosyltransferase and excreted in the urine. (L133)
- Where is dibutyl phthalate found?
- Dibutyl phthalate was detected in 16 of 43 surface water samples collected through out Korea in 2002 at a maximum of 1.1 ug/L (14). Dibutyl phthalate was detected in the Tama River at 0.71-3.14 ppb (15) and Shizuoka River at an average of 1.39 ppb (16), both rivers in Japan. Dibutyl phthalate was detected in Tuchibuchi River in Japan (17).
