Acetyl tributyl citrate, the most widely used phthalate
In particular, acetyl tributyl citrate (ATBC), an industrial plasticizer widely used in products such as food wrap, vinyl toys, and pharmaceutical excipients, strongly activated human and rat SXR. ATBC increased CYP3A4 messenger RNA (mRNA) levels and enzyme activity in the human intestinal cells but not in human liver cells.
Phthalate alternative may harm brain development and health
Growing concerns over the potential health effects of exposure to phthalates have led to a search for safer alternatives. Researchers found that the chemical acetyl tributyl citrate (ATBC) might
CPSC Staff Statement on University of Cincinnati Report
“Toxicity Review for Acetyl Tri-n-butyl Citrate (ATBC)” 1. October 2018 . The U.S. Consumer Product Safety Commission (CPSC) contracted with the University of Cincinnati to conduct toxicology assessments for six dialkyl o-phthalate (o-DAP) substitutes: acetyl tri-n-butyl citrate (ATBC); bis(2-ethylhexyl) adipate (DEHA); di-2-
Analysis of the most appropriate risk management option (RMOA)
tributyl ester Acetyl tributyl citrate Type of substance Mono-constituent Multi-constituent UVCB Structural formula: 1.2 Similar substances/grouping possibilities The tributyl citrate (TBC, EC No 201-071-2) registrant proposed in its dossier a category approach with TEC, ATEC, ATBC and ATEHC (see FR RMOA on TBC). The read-
Acetyl tributyl citrate | C20H34O8
Acetyl tributyl citrate | C20H34O8 - PubChem compound Summary Acetyl tributyl citrate Cite Download Contents 1 Structures 2 Names and Identifiers 3 Chemical and Physical Properties 4 Spectral Information 5 Related Records 6 Chemical Vendors 7 Food Additives and Ingredients 8 Pharmacology and Biochemistry 9 Use and Manufacturing
- What is acyl tributyl citrate / ATBC?
- What is Acetyl tributyl citrate / ATBC?
- What is Acetyl tributyl citrate / ATBC?
- Acetyl tributyl citrate is an organic substance with a chemical formula of C20H34O8. It is a colorless, odorless, oily liquid, soluble in most organic solvents, but insoluble in water.
- What are the metabolites of 14c-acetyl tributyl citrate?
- Both the absorption and metabolism of 14C-Acetyl tributyl Citrate proceeded rapidly, and the following metabolites were identified: acetyl citrate, monobutyl citrate, acetyl monobutyl citrate, dibutyl citrate, and acetyl dibutyl citrate. Membrane CIR ingredient: Acetyl Tributyl Citrate
- What is acetyl trityl citrate (ATBC)?
- IDENTIFICATION AND USE: Acetyl tributyl citrate (ATBC) is a colorless liquid. It is the most widely used phthalate substitute plasticizer. It is used in products such as food wrap, vinyl toys, and pharmaceutical excipients. It is also used as a flavor ingredient in non-alcoholic beverages.
- Is acetyl tributyl citrate aging-induced toxicity?
- The aim of this study was to apply a network toxicology strategy to investigate the potential toxicity and the molecular mechanisms underlying the aging-induced toxicity of acetyl tributyl citrate (ATBC). Utilizing the ChEMBL, SwissTargetPrediction, and CellAge databases, we identified 32 potential targets associated with ATBC exposure and aging.
- Where can I find information about acetyl tributyl citrate?
- Approved in the USA for direct food contact in food films. J & K SCIENTIFIC LTD. Acetyl tributyl citrate (CAS 77-90-7) information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices, suppliers, SDS and more, available at Chemicalbook.
- How many workers are exposed to acetyl tributyl citrate?
- NIOSH (NOES Survey 1981-1983) has statistically estimated that 106,672 workers (98,182 of these are female) are potentially exposed to acetyl tributyl citrate in the US (1).