Guideline on the use of phthalates as excipients in human
The high - molecular-weight phthalate polymers; CAP, HPMCP and PVAP, are polymers modified by esterification with ortho-phthalic acid groups. The phthalates restricted from toys and food articles in the EU due to evidence of endocrine disruption, have been the low -molecular weight ortho- phthalates.
Phthalates in Cosmetics | FDA
Phthalates are used in a variety of cosmetics and personal care products. Phthalates are chemical compounds developed in the last century that are used to make plastics more durable. These
Toxicity review of diethyl phthalate (DEP) - U.S. Consumer
The purity of DEP can achieve 99% or greater using current manufacturing processes (HSDB, 2009). The remaining fraction of the DEP commercial mixture can also contain impurities such as isophthalic, terephthalic acid, and maleic anhydride (Harris et al., 1997; ATSDR, 1995).
Hazards of diethyl phthalate (DEP) exposure: A systematic
Background. Diethyl phthalate (DEP) is widely used in many commercially available products including plastics and personal care products. DEP has generally not been found to share the antiandrogenic mode of action that is common among other types of phthalates, but there is emerging evidence that DEP may be associated with other types of health effects.
OPINION ON PHTHALATES IN COSMETIC PRODUCTS - European Commission
diethyl phthalate (DEP) in perfume was from 0.4 to 22299 mg/kg or 2.23% with a median concentration of 1073 mg/kg. These concentrations are within the range allowed for DEP use in perfumes. The SCCP does not see any need to update its previous opinions (SCCNFP/411/01 adopted during the 20th plenary meeting of 4 June 2002 and reiterated in
- What is diethyl phthalate?
- Diethyl phthalate is a chemical compound is a diethyl ester of phthalic acid that belongs to the phthalate ester family. It is a clear, colourless liquid that is slightly denser than water and has low volatility. It is commonly synthesized via the Oxo or Ald-Ox processes and is also known as phthalol or solvanol.
- Why do companies invest in diethyl phthalate chemicals?
- Several companies are funding to expand their product portfolios of diethyl phthalate chemicals and serve a wide range of industries. Manufacturers are investing in the research and development of new and innovative products which comply with various environmental and health regulations.
- What is the demand for diethyl phthalate in plasticizers?
- Increasing demand for diethyl phthalate in plasticizers for the manufacturing of packaging films, automotive parts, tools, and plastic films are expected to bolster the growth of the product market during the forecast period. Plastic films and bubble wraps are two common packaging materials used in the packaging industry.
- What is the global diethyl phthalate market size?
- According to the FMI analysis, the global diethyl phthalate market witnessed a CAGR of 1.9% during the historical period of 2018 to 2022. The market stands at US$ 138.1 Million in 2022. The industry is anticipated to foresee an increased CAGR of 2.2% during the forecast period of 2023 to 2033.
- What does diethyl phthalate taste like?
- Diethyl phthalate is produced in the reaction of phthalic anhydride with ethanol in the presence of concentrated sulphuric acid catalyst. Clear, colorless, oily liquid with a mild, chemical odor. Bitter taste. Virtually odorless when pure ("Perfumery grade" of commercial Diethyl phthalate). Very bitter taste in weak hydro-alcoholic solution.
- What is the phthalate removal efficiency of DEHP?
- Global phthalate removal The WWTP average removal efficiency for DEHP was 78% from May 22 to 28, 2006 ( Table 3 ). A similar DEHP elimination ratio (75%) was observed in Canada with the same treatment device ( Fernandez et al., 2007 ).
