Pharmacokinetics and Metabolism of Acetyl Triethyl Citrate, a
Acetyl triethyl citrate (ATEC) is a water-soluble plasticizer used in pharmaceutical plasticized polymers. In this study, the pharmacokinetics and metabolism of ATEC were investigated using liquid chromatography-tandem mass spectrometry (LC-MS/MS) in rats. Plasma protein precipitation with methanol was used for sample preparation.
Effect of acetylated citrate plasticizer on mechanical
In this work, the effects of acetylation modification on the plasticization properties of citrates (triethyl citrate (TEC), acetyl triethyl citrate (ATEC), tributyl citrate (TBC) and acetyl tributyl citrate (ATBC)) were investigated by using a combination of characterization techniques and molecular dynamics (MD) simulation.
AQUACOAT ECD: CRITICAL FORMULATION ATTRIBUTES OF PLASTICIZER
ATTRIBUTES OF PLASTICIZER. Technical Memorandum. TM HO73-1. Type of plasticizers. Plasticizers can be divided into hydrophilic (water-soluble) and . hydrophobic (water-insoluble) (Table 1). Water-soluble plasticizers such as TEC (triethyl citrate) produce a hydrophilic film and faster drug dissolution than water-insoluble plasticizers such as DBS
Pharmacokinetic Properties of Acetyl Tributyl Citrate, a
Acetyl tributyl citrate (ATBC) is an (the Food and Drug Administration) FDA-approved substance for use as a pharmaceutical excipient. It is used in pharmaceutical coating of solid oral dosage...
functional plasticizers - Vertellus
Our range of citrate and sebacate ester plasticizers are effective in both aqueous and solvent based coating systems. Citroflex Citrate Ester Plasticizers. Acetyl Tributyl Citrate (ATBC) NF. Acetyl Triethyl Citrate (ATEC) NF. Tributyl Citrate (TBC) NF. Triethyl Citrate (TEC) NF. Sebacate Ester Plasticizers. Dibutyl Sebacate (DBS) NF.
- What is triethyl O acetylcitrate used for?
- Triethyl O-Acetylcitrate is used in the preparation of poly (lactic) acid biodegradable and flexible films, acting as a plasticizer. Also used in the synthesis of control-release capsules containing polymeric coatings. ATEC is produced by the reaction of citric acid triethyl ester with acetic acid anhydride.
- How is acetyltriethyl citrate made?
- ATEC is produced by the reaction of citric acid triethyl ester with acetic acid anhydride. It is used as a solvent plasticizer for cellulose nitrate and cellulose acetate. Acetyltriethyl citrate is prepared by the esterification of citric acid with ethanol followed by acylation with acetic anhydride. Aqueous-based pharmaceutical coat- ings.
- What is acetyltriethyl citrate?
- n 20/D 1.439 (lit.) storage temp. Soluble 1 in 140 of water; miscible with acetone, ethanol, and propan-2-ol. Acetyltriethyl citrate occurs as a clear, odorless, practically colorless oily liquid. Triethyl O-Acetylcitrate is used in the preparation of poly (lactic) acid biodegradable and flexible films, acting as a plasticizer.
- What is triethyl 2-acetylcitrate used for?
- Triethyl 2-acetylcitrate is widely used in hydrophilic adhesives for medications and in biodegradable composition for papermaking and nonwoven production. Acetyltriethyl citrate is used to plasticize polymers in formulated pharmaceutical coatings.
