PHARMACEUTICALLY USED PLASTICIZERS: A REVIEW - ResearchGate
The concentration of plasticizer affects the strength of coating films, overall integrity of drug products and drug release characteristics in therapeutic pharmaceutical dosage forms. 1, 2 The...
PHARMACEUTICALLY USED PLASTICIZERS: A REVIEW
example of good compatibility due to similar chemical structure (polarity, shape, size) is the oldest known plasticizer- polymer system: camphor and cellulose
Plasticizer - an overview | ScienceDirect Topics
Common plasticizers used in ceramic formulations include phthalates, such as dibutyl phthalate (DBP), and poly (ethylene glycol) (PEG), which have molecular weights in the range 100–1000 gmol 1. Factors that affect compatibility include the polarity, size, and shape of the plasticizing molecules.
[PDF] Pharmaceutically Used Plasticizers | Semantic Scholar
The extensive use of polymers in medical and pharmaceutical applications including particularly packaging, medical devices, drug carriers and coatings has caused a substantial demand for the proper plasticizers. Although there are many plasticizers used in the chemical industry, only a few of them have been approved for pharmaceutical applications.
Pharmaceutically Used Plasticizers - ResearchGate
Various materials such as glycerin (Gly), propylene glycol (PG), and polyethylene glycol (PEG) are used to plasticize gelatin capsules (Gullapalli & Mazzitelli, 2017;Langmaier et al., 2008;Park...
- Are plasticizers suitable for pharmaceutical applications?
- The extensive use of polymers in medical and pharmaceutical applications including particularly packaging, medical devices, drug carriers and coatings has caused a substantial demand for the proper plasticizers. Although there are many plasticizers used in the chemical industry, only a few of them have been approved for pharmaceutical applications.
- What are the properties of plasticizers?
- Flexibility, Endurance, Resistibility and Stability which are suitable properties of formulation could be easily achieved by using plasticizers which ultimately imparted desired characteristic in the formulation by the radical use of this excipient.
- Are natural-based plasticizers suitable for pharmaceutical and medical applications?
- The natural-based plasticizers characterized by low toxicity and low migration are required nowadays not only for pharmaceutical and medical applications. In this respect, most of traditional plasticizers are not applicable in this area.
- Are plasticizers a low molecular weight non-volatile additive?
- The primary role of all plasticizers as low molecular weight non-volatile additives is to improve the flexibility and processability of polymers by lowering the second order transition temperature (glass transition temperature, Tg) (Rosen, 1993).
- Why do we need plasticizers?
- 1. Introduction The extensive use of polymers in medical and pharmaceutical applications including particularly packaging, medical devices, drug carriers and coatings has caused a substantial demand for the proper plasticizers.
- Why do polymers use plasticizers?
- Plasticizers can be added to polymers to make them more flexible. Plasticizers are small lubricating behaviour, and adhesive property of polymeric films. drug release performance. WHAT IS A PLASTICIZER?
- to increase its flexibility. The plasticizer gets between makes the material more flexible. T he polymer will where flexibility is required.
