Eastman Plasticizers for Medical Products Used in Flexible PVC
Medical. Eastman has a long history of producing innovative plasticizers for medical. Today, our products improve the flexibility, durability, longevity, and utility of medical packaging, devices, and materials worldwide. You’ll find our plasticizers throughout hospital corridors, in pharmaceutical labs, and in doctors’ offices—from
A Comparison of Plasticizers for Use in Flexible Vinyl
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A comparison of plasticizers for use in flexible vinyl
Download Citation | On Jan 1, 2001, R.C. Adams published A comparison of plasticizers for use in flexible vinyl medical products | Find, read and cite all the research you need on ResearchGate
Eliminating DEHP Plasticizer in Medical-Grade PVC
By comparison, polymeric plasticizers have molecular weights that are typically four times as great. Fig. 3 – Plasticizer Solubility Weight Change of 75 Shore A PVC After 24 Hours in 2% Salt Solution. The families classified as monomeric plasticizers are quite diverse:
Plasticizers – Benefits, Trends, Health, and Environmental
Around 90 % of all plasticizers are used in the production of flexible polyvinyl chloride (PVC), also known as vinyl. The main applications for flexible PVC include flooring and wall coverings, roofing membranes, electrical cable and wire insulation, automotive applications, medical devices, synthetic leather goods, and so forth.
- Can plasticizers be quantified in medical devices?
- For plasticizer quantification in MDs we chose to limit the sample quantity considering that the limit of quantification obtained on 10 mg was enough. Indeed we wanted to be able to analyze very small PVC samples from medical devices, so the less we used for extraction, the better. 3.4. Medical device tests
- Are medical devices made of flexible plasticized polyvinylchloride (PVC)?
- This study provides advices and directions on the routine use of the methods. A wide variety of medical devices (MDs) used in hospitals are made of flexible plasticized polyvinylchloride (PVC).
- Does plasticizer release a PVC MD into a simulant solution?
- We then tested the developed method on 32 PVC MDs used in our hospital and evaluated the plasticizer release from a PVC MD into a simulant solution during a 24 h migration test. The results showed a predominance of TOTM in PVC MDs accompanied by DEHP (<0.1% w/w), DEHT, and sometimes DEHA.
- What are the alternative plasticizers for PVC MDS?
- This resulted in the commercialization of PVC MDs plasticized with the DEHP alternative plasticizers tri-octyl trimellitate (TOTM), di- (2-ethylhexyl) terephthalate (DEHT), di-isononyl cyclohexane-1,2-dicarboxylate (DINCH), di-isononyl phthalate (DINP), di- (2-ethylhexy) adipate (DEHA), and Acetyl tri- n -butyl citrate (ATBC).
- Which plasticizer is most commonly used in medical devices?
- TOTM is the plasticizer most frequently used in the MDs studied (45%) followed by DEHP (29%), DINCH (16%), DINP (7%), ATBC (3%), and DEHA (3%). But the repartition is very disparate according to the types of MD. Fig. 4. Distribution of the majority plasticizers in the 32 medical devices analyzed according to the type of MD.
- Do plasticizers migrate from medical devices?
- In order to evaluate patient exposure risk, plasticizer migration from medical devices must be assessed. An analytical method which allows the identification and the quantification of these plasticizers in the MD itself is therefore needed.
