A new pharmacological function of phthalate ester plasticizer
Phthalate ester plasticizers have a new pharmacological function in selective suppression of the growth of tumor cells both in vitro and in vivo. References (4) T.J.B. Gray et al. Species difference in the testicular toxicity of phthalate esters Toxic. Lett. (1982) R.D. White et al.
A new pharmacological function of phthalate ester plasticizer
A new pharmacological function of phthalate ester plasticizer Leuk Res. 1993 Nov;17(11):1013-6.doi: 10.1016/0145-2126(93)90050-u. Authors C T Wu 1 , Y M Jiang, J R Cao, H H Xue Affiliation 1Department of Experimental Hematology, Beijing Institute of Radiation Medicine, China. PMID: 8231228
The effects of phthalate ester exposure on human health: A
Abstract. Phthalate esters (PAEs) are one of the most widely used plasticizers in polymer products and humans are increasingly exposed to them. The constant exposure to PAEs-contained products has raised some concerns against human health. Thus, the impacts of PAEs and their metabolites on human health require a comprehensive study for a better
Phthalates Toxicity - StatPearls - NCBI Bookshelf
Phthalates are a broad group of compounds that serve as plasticizers to impart flexibility and durability to products.[1][2] They are ubiquitous in the environment as millions of tons of plastic are produced yearly worldwide.[3] The toxicology and biochemical interplay of phthalates with human physiology has received increasing attention as studies have begun to show the negative effects of
Di(2-propylheptyl) Phthalate: A New Plasticizer Choice
BASF Corp., 100 Campus Dr., Florham Park, New Jersey 07932 Science and practice have proven that phthalic acid esters are among the most functional plasticizers for
- Are phthalate esters a good plasticizer?
- Phthalate esters (PAEs) are the most important and widely used plasticizers (Erythropel et al., 2014) as they can enhance flexibility and elasticity, and therefore improving the quality of plastic polymers.
- What is a phthalic acid ester (PAE)?
- Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or the National Institutes of Health. Phthalic acid esters (PAEs) are a class of lipophilic chemicals widely used as plasticizers and additives to improve various products’ mechanical extensibility and flexibility.
- Which phthalate is used as a plasticizer?
- Traditionally, phthalate esters, most prominently, di (2-ethylhexyl) phthalate [DEHP], have been used as plasticizers. DEHP is produced from two inexpensive precursors, phthalic acid and 2-ethylhexanol. Phthalic acid is obtained from the oxidation of o -xylene, the least useful of the mixed xylenes from the reforming of naphtha .
- Are phthalate esters antimicrobial?
- In addition, phthalate esters’ insecticidal activity protects plants from being consumed by insects [17, 129, 137], not to mention the fact that the antimicrobial activity of PAEs may reduce the damage caused by pathogenic fungi and bacteria [17, 107, 108, 118, 119].
- Are non-phthalate plasticizers effective?
- The response to the need for non-phthalate plasticizers that are effective, nonmigrating and nontoxic has focused on the development of plasticizing compounds derived from biomaterials or biobased materials [7 – 9]. Most often, these have been designed for use in PVC [10 – 12].
- Are phthalate-containing products a health hazard?
- With such extensive application of phthalate-containing products, PAEs have attracted increasing attention as environmental and biomedical pollutants, which may invisibly enter the human body through airborne transmission, skin contact, and food chain transmission, constituting potential health and ecological system threats .
