Acetyl tributyl citrate, the most widely used phthalate
In particular, acetyl tributyl citrate (ATBC), an industrial plasticizer widely used in products such as food wrap, vinyl toys, and pharmaceutical excipients, strongly activated human and rat SXR. ATBC increased CYP3A4 messenger RNA (mRNA) levels and enzyme activity in the human intestinal cells but not in human liver cells.
Phthalate alternative may harm brain development and health
Acetyl tributyl citrate, a leading phthalate alternative, found to disrupt neuron-like cells Date: March 28, 2025 Source: American Society for Biochemistry and Molecular Biology Summary:...
Analysis of the most appropriate risk management
tributyl ester Acetyl tributyl citrate Type of substance Mono-constituent Multi-constituent UVCB Structural formula: 1.2 Similar substances/grouping possibilities The tributyl citrate (TBC, EC No 201-071-2) registrant proposed in its dossier a category approach with TEC, ATEC, ATBC and ATEHC (see FR RMOA on TBC). The read-
CPSC Staff Statement on University of Cincinnati Report
“Toxicity Review for Acetyl Tri-n-butyl Citrate (ATBC)” 1. October 2018 . The U.S. Consumer Product Safety Commission (CPSC) contracted with the University of Cincinnati to conduct toxicology assessments for six dialkyl o-phthalate (o-DAP) substitutes: acetyl tri-n-butyl citrate (ATBC); bis(2-ethylhexyl) adipate (DEHA); di-2-
Registration Dossier - ECHA - Europa
Reference substance name: Tributyl O-acetylcitrate EC Number: 201-067-0 EC Name: Tributyl O-acetylcitrate CAS Number: 77-90-7 Molecular formula: C20H34O8
