Phthalate alternative may harm brain development and health
ATBC had emerged as a leading phthalate alternative as companies sought to shift away from phthalates; it is currently used in a variety of materials and products, including food and food...
Alternative Plasticizers As Emerging Global Environmental and
There are a considerable number of alternative plasticizers in employment, without any toxicological data available (dibutyl adipate, diethylene glycol dibenzoate, and bis-2-ethylhexyl sebacate, to name a few).
Alternative Plasticizers As Emerging Global Environmental and
Thereare about 30000 chemicals can potentially be utilized as plasticizers.1Phthalate plasticizers are a commonly utilized compound, comprising up to 85% of the total plasticizers in the market.1Phthalate plasticizers have been regardedas hazardous compounds due to numerous reports based on its toxicological eects, including bioaccumulation
Non-DEHP PVC and Medical Devices | Spectrum Plastics
ATBC is the common plasticizer for enteral applications, whereas BTHC is most often used in blood storage bags and catheters. The BTHC, however, is a very expensive plasticizer. DOA or dioctyl adipate, has the best efficiency of the common plasticizers and by far the best low temperature properties.
Phthalate and alternative plasticizers in indwelling medical
Alternative plasticizers 1. Introduction Pediatric intensive care relies heavily on the use of soft and flexible indwelling medical devices, like intravenous catheters and cannulas, which are indispensable to administer medicines and parenteral feeding to the patient.
- What are alternative plasticizers?
- Extensive research has been performed to identify alternatives for PEs. Currently, many different alternative plasticizers exist including adipates, benzoates, citrates, cyclohexane dicarboxylic acids, epoxidized vegetable oils, glycerol acetylated esters, phosphate esters, sebacates, terephthalates and trimellitates.
- Do alternative plasticizers metabolize phthalates and DINCH?
- For instance, the human metabolism of phthalates and DINCH is well known. Therefore, exposure to these substances can be well assessed by measuring relevant metabolites in human matrices like blood or urine. Unfortunately, this has not been done for all relevant alternative plasticizers.
- Are alternative plasticizers safe?
- Toxicity profiles were extensive but still showed data gaps, mostly regarding carcinogenicity and endocrine disruption (Table 1 A). According to current knowledge, the use of alternative plasticizers seems to be of low risk for humans as calculated risk ratios were mostly well below 1.
- Are there alternative plasticizers in the indoor environment?
- Generally, alternative plasticizers can be expected in various exposure matrices in the indoor environment, although only very few exhibit strong partitioning to indoor air. Instead, it is likely that many alternatives will be detected in dust and/or food due to their low volatility and relatively high hydrophobicity.
- Are alternative plasticizers phthalate or phosphate esters?
- Additionally, some substances are not exclusively being used as plasticizers. For example, phosphate esters have also been widely used as flame retardants (Marklund et al., 2003, Wei et al., 2015). In this work, we consider the term “alternative plasticizer” as a synonym for non-phthalate plasticizers.
- What are plasticizers?
- 1. Introduction Plasticizers are chemical additives that provide durability, elasticity and flexibility of polymeric products (Wilkes et al., 2005).