In vitro cytotoxic effects of DEHP-alternative plasticizers
Since the plasticizer DEHP was classified as CMR 1B, manufacturers have used various alternative plasticizers with high molecular weights or different solubility properties, such as other phthalates, trimellitates, citrates, alkyl sulfonic phenyl esters (ASEs), C10-21-alkanes, acetylated monoglycerides of hydrogenated castor oil (COMGHAs), or
Alternative Plasticizers As Emerging Global Environmental and
Plasticizers are synthetic chemicals that are commonly used in polyvinyl chloride (PVC) based products, food packaging, children’s toys, medical devices, and adhesives. There are about 30 000 chemicals can potentially be utilized as plasticizers.
Advanced Medical-Grade Compounds - PVC plasticizers - Tekni-Plex
Primary alternatives include monomeric plasticizer (all esters) manufactured by the reaction of selected acids with selected alcohols. Due to the polarity of the ester groups these plasticizers have a high level of compatibility with the PVC base polymer. These include:
What is the best alternative to DEHP for medical-grade PVC
“There are a number of alternative plasticizers on the market. While Teknor Apex is best known as a manufacturer of medical-grade PVC compounds, we also produce some of these plasticizers,” notes Galland.
Comparison of Various Plasticizers In Medical PVC Materials
Alternative plasticizers for evaluation TOTM (trioctyl trimellitate) TOTM is an ester produced by reacting trimellitic acid with 2-ethyl hexanol. Manufacturers could consider it the plasticizer of choice for drug infusion or chemotherapy materials because of its significant chemical resistance. It has extremely low volatility.
- Are there phthalates and non-phthalate plasticizers in the coastal environment of Korea?
- Conclusions This is the first nation-wide survey of phthalates and non-phthalate plasticizers in the coastal environment of Korea. Phthalates and alternative plasticizers were detected in all sediment samples from the coastal zone of Korea. DEHP and DEHT were the dominant phthalates and NPPs, respectively.
- Are phthalates and non-phthalate plasticizers found in coastal sediment?
- Korea is the world's largest consumer of plastic, with increasing production and consumption ( European Plastics and Rubber Machinery, 2016 ). The present study assesses the occurrence, spatial distribution, and potential contamination sources of phthalates and non-phthalate plasticizers in coastal sediment from Korean coastal waters.
- Are non-phthalate plasticizers contaminating the coastal environment?
- All NPPs were detectable in all sediment samples, indicating widespread contamination of the coastal environment by these plasticizers. DEHA and DEHT were detected in almost all sediment samples (detection rate: 98%), also suggesting major contamination by non-phthalate plasticizers.
- How are phthalates and NPPs distributed along Korea's Coast?
- The spatial distribution of phthalates and NPPs along Korea's coast is governed by harbor-zone activities and sedimentary organic carbon. Significant correlations were observed among the compounds of phthalates and NPPs in sediments, suggesting similar sources and environmental behavior in coastal environments.
- Do phthalates and non-phthalate plasticizers pose ecological risk to benthic organisms?
- Given the occurrence of phthalates and non-phthalate plasticizers, including DEHP, further studies are required to identify the contamination sources and assess the ecological risk to benthic organisms posed by these contaminants in coastal environments. Fig. 5 Cumulative distribution (%) of DEHP concentrations measured in sediments from.
- Are phthalate plasticizers contaminating the environment?
- DEHA and DEHT were detected in almost all sediment samples (detection rate: 98%), also suggesting major contamination by non-phthalate plasticizers. The occurrence of phthalates in the environment is related to production and consumption in industrial markets ( Gao and Wen, 2016 ).