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Summary TOTM - trioctyl trimellitate - phthalate free plasticizer alternative. Usage: Wires & Cabler Leather Cloths Gloves Shoes Construction materials PVC Plastisols Description TOTM has low volatility and low migration and its electric resistivity and heat resistance are excellent.

DOA - dioctyl adipate - phthalate free plasticizer alternative. Description Dioctyl adipate DOA plasticizer (Bis (2-Ethylhexyl) Adipate) is a light colored, oily liquid generally used as a plasticizer for PVC. It can be used alone or blended with other plasticizers.

TI/N-CPN/IP Plastomoll DOA / June 2025 Page 3 of 4 Plastomoll DOA Description Plastomoll DOA is a highly efficient plasticizer which imparts excellent low temperature flexibility and resistance to impact to the base resin. For these reasons it finds wide use in polymeric systems based on vinyl, nitrocellulose and rubber.

The three prominent PVC plasticizers are DEHP, DINP and DIDP and they are all dialkyl ortho-phthalates. Over the last 60 years, the most common plasticizer used to soften PVC compounds used for medical devices has been DEHP Di-2 ethyl hexyl phthalate. DEHP is economical and offers excellent performance (e.g., compatibility with PVC, plasticizer

All 10 potential alternatives are used today as plasticisers in medical devices. However, it is very important to emphasise that the report does not assess whether the alternatives are technically applicable in all types of medical devices, which today are plasticised with DEHP.