Alternative plasticizer - GYC TOTM | ChemSec Marketplace

                                               
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Alternative plasticizer - Metalest DOA | ChemSec Marketplace

                                               
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Alternatives to phthalates to medical devices

                                               
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DOA Plasticizer | Eastman

                                               
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Cost Effective Regulatory Compliant Plasticizer Alternatives

                                               
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  • Are there alternative plasticizers?
  • There are a considerable number of alternative plasticizers in employment, without any toxicological data available (dibutyl adipate, diethylene glycol dibenzoate, and bis-2-ethylhexyl sebacate, to name a few).
  • Where can I find toxicological data for alternative plasticizers?
  • For all selected alternative plasticizers, toxicological information is available to a certain extent. Since these substances are produced in high volumes, toxicological data are required in the EU and could be found in the ECHA database for registered substances (ECHA, 2014b).
  • Are alternative plasticizers phthalate or phosphate esters?
  • Additionally, some substances are not exclusively being used as plasticizers. For example, phosphate esters have also been widely used as flame retardants (Marklund et al., 2003, Wei et al., 2015). In this work, we consider the term “alternative plasticizer” as a synonym for non-phthalate plasticizers.
  • Do alternative plasticizers metabolize phthalates and DINCH?
  • For instance, the human metabolism of phthalates and DINCH is well known. Therefore, exposure to these substances can be well assessed by measuring relevant metabolites in human matrices like blood or urine. Unfortunately, this has not been done for all relevant alternative plasticizers.
  • Are alternative phthalate plasticizers toxic?
  • Most long-term DNELs of alternative plasticizers are relatively high compared to DEHP (one of the most toxic phthalate plasticizers). Also other phthalates (DINP, DIDP, DPHP) were less toxic than DEHP, having higher DNELs. For DBA, COMGHA, DOS and DBS no hazard was identified due to the extremely low toxicities measured.
  • What are plasticizers?
  • 1. Introduction Plasticizers are chemical additives that provide durability, elasticity and flexibility of polymeric products (Wilkes et al., 2005).