Impact of alternative materials to plasticized PVC infusion
Surface analysis by ATR-FTIR highlighted the presence of a plasticizer (that could be attributed to Tris (2-Ethylhexyl) Trimellitate (TOTM)) in the coextruded SEBS layer of PVC/SEBS, which could have influenced drug sorption, probably as a consequence of a migration from the PVC layer.
Alternative plasticizer - TOTM | ChemSec Marketplace
TOTM Plasticizer (Tris (2-Ethylhexyl) Trimellitate) is the ideal PVC plasticizer for use in applications where low volatility is of supreme importance. For example, these applications include wire and cable insulation and interior automotive. Possible replacement to Phthalates. Supplier Nan Ya Plastics Visit website View more from this supplier
TOTM - plasticizer | ChemSec Marketplace
TOTM Plasticizer (Tris (2-Ethylhexyl) Trimellitate) is the ideal PVC plasticizer for use in applications where low volatility is of supreme importance. For example, these applications include wire and cable insulation and interior automotive. Possible replacement to Phthalates. Supplier UPC Group Visit website View more from this supplier
Phthalate and alternative plasticizers in indwelling medical
Results indicated that DEHP was predominantly present as plasticizer (60 of 97 samples), followed by bis(2-ethylhexyl) adipate (DEHA, 32 of 97), bis(2-ethylhexyl) terephthalate (DEHT, 24 of 97), tris(2-ethylhexyl) trimellitate (TOTM, 20 of 97), and tributyl-O-acetyl citrate (ATBC, 10 of 97).
TOTM (Tris (2-Ethylhexyl) Trimellitate) Plasticizer | Eastman
Product description Eastman TOTM Plasticizer (Tris (2-Ethylhexyl) Trimellitate) is the ideal PVC plasticizer for use in applications where low volatility is of supreme importance. These applications include wire and cable insulation (TOTM-CA) and interior automotive.
- What is plasticizer Tris (TOTM) trimellitate (TOTM)?
- For PVC, PVC/PE, PVC/PU and PVC/SEBS, the PVC matrix was plasticized with plasticizer tris (2-ethylhexyl) trimellitate (TOTM) (manufacturer information).
- Is tris 2 ethylhexyl trimellitate safe?
- Objectives: An alternative plasticizer, tris (2-ethylhexyl) trimellitate (TOTM), was developed from di- (2-ethylhexyl) phthalate (DEHP) for use in medical tubing. However, little is known about the biological effects of TOTM and thus its safety is not yet well-established.
- What is Tris (ethylhexyl) trimellitate?
- Tris (2-ethylhexyl) trimellitate. Eastman TOTM plasticizer by Eastman acts as a plasticizer. Used in applications where low volatility is of supreme importance. Has unique low migration properties and extraction resistance properties.
- What is Tris (2-ethylhexyl)trimellitate?
- Tris (2-ethylhexyl)trimellitate (TOTM) is used as an alternative plasticizer of polyvinyl chloride (PVC) medical devices. A method for the determination of TOTM released from PVC medical devices into intravenous preparations was developed, which uses liquid chromatography-tandem mass spectrometry (LC–MS/MS).
- What is Eastman TOTM plasticizer?
- View technical datasheet of Eastman TOTM plasticizer. It is a plasticizer used in applications where low volatility is of supreme importance.
- Can alternative plasticizers migrate from the PVC matrix?
- Alternative plasticizers like Diisononyl Phtalate (DINP), Di- (2-Ethylhexyl) Phtalate (DEHT), 1,2-cyclohexane dicarboxylic acid diisononyl ester (DINCH) or Tris (2-Ethylhexyl) trimellitate (TOTM) were then used in the manufacturing of medical devices 18, yet all those alternatives plasticizers can potentially migrate from the PVC matrix.
