Exposure to organophosphate esters, phthalates, and
In addition, phthalates have been replaced by other alternative plasticizers (APs), such as 1,2-cyclohexane dicarboxylic acid, diisononyl ester (DINCH), and di-2-ethylhexyl terephthalate (DEHTP). Compared to conventional phthalates, much less information is currently available about potential health consequences of these substituting chemicals.
Exposure to organophosphate esters, phthalates, and
Abstract Exposure to endocrine disrupting chemicals is suggested to be responsible for the development or progression of uterine fibroids. However, little is known about risks related to emerging chemicals, such as organophosphate esters (OPEs) and alternative plasticizers (APs).
Chemicals in Household Plastics May Raise Risk for Fibroids
TUESDAY, Nov. 15, 2025 (HealthDay News) -- Uterine fibroids can cause uncontrolled bleeding and infertility in women, and now a new study finds an unexpected culprit: Toxic chemicals called...
Exposure to organophosphate esters, phthalates, and
In this study, urinary concentrations of metabolites of DEHP and the non-phthalate plasticizer di-2-ethylhexyl terephthalate (DEHTP) were significantly associated with uterine fibroids in...
Exposure to Phthalates and Alternative Plasticizers Is
The total concentration of phthalate and alternative plasticizer metabolites was creatinine standardized using the following formula to address urinary dilution as stated in previous studies: Total [phthalate metabolites] = 100× phthalate (ng/mL)/creatinine (mg/dL) [ 29, 30 ].
- Are organophosphate esters and alternative plasticizers associated with uterine fibroids?
- However, little is known about risks related to emerging chemicals, such as organophosphate esters (OPEs) and alternative plasticizers (APs). A case-control study was conducted to investigate whether exposures to OPEs, APs, and phthalates, were associated with uterine fibroids in women of reproductive age.
- Can endocrine disrupting chemicals cause uterine fibroids?
- Electronic address: kyungho@snu.ac.kr. Exposure to endocrine disrupting chemicals is suggested to be responsible for the development or progression of uterine fibroids. However, little is known about risks related to emerging chemicals, such as organophosphate esters (OPEs) and alternative plasticizers (APs).
- What chemicals are associated with presence of uterine fibroids?
- Several chemicals have been reported to be associated with presence of uterine fibroids in epidemiological studies, which include di (2-ethylhexyl) phthalate (DEHP) metabolites ( Fu et al., 2017; Huang et al., 2010; Kim et al., 2016; Sun et al., 2016) and environmental phenols, such as bisphenol A and nonylphenol ( Shen et al., 2016 ).
