Application of Carrier and Plasticizer to Improve the
Application of Carrier and Plasticizer to Improve the Dissolution and Bioavailability of Poorly Water-Soluble Baicalein by Hot Melt Extrusion February 2014 AAPS PharmSciTech 15 (3) DOI:...
Application of Carrier and Plasticizer to Improve the
Proper carriers and plasticizers were selected by calculating the Hansen solubility parameters, evaluating melting processing condition, and measuring the solubility of obtained melts. The characteristic of solid dispersions prepared by HME was evaluated.
Research Article
Application of Carrier and Plasticizer to Improve the Dissolution and Bioavailability of Poorly Water-Soluble Baicalein by Hot Melt Extrusion Yilan Zhang, 1 Rui Luo, 1 Yi Chen, 1 Xue Ke, 1,2
Polymer inclusion membrane applications for transport
Plasticizers are used both in plasticizing the polymer matrix and as a solvent for the carrier ( Pospiech, 2013 ). In addition, due to their chemical and mechanical properties, they provide stability and flexibility to the membrane and strengthen membrane performance.
Application of TPGS as an efflux inhibitor and a plasticizer
In our study, PVP VA64 was selected as the carrier, and TPGS was used as a plasticizer to prepare BPT-SD, which can improve the dissolution rate of BAC, thereby increasing its oral bioavailability. The HME process is a new, environmentally friendly, and efficient preparation method, that can render BAC highly dispersed in the carrier and
- Why are plasticizers still produced in Iran?
- Abstract—Iran is one of the main producers and consumers of plasticizers in the Middle East and Asia, but due to imposed sanctions, unfortunately Iran was deprived from the research and development in this industry. As a result, this has caused continuing the production of harmful plasticizers in Iran.
- Why is DOP still used in Iran?
- Unlike other countries, DOP is still being used in Iran, because new plasticizers are not produced, although, in some cases they are imported. B. Importance of research Right now, it seems it is necessary to raise the level of awareness of the community and encouraging manufactures to produce substitute products.
- What are plasticizers & how do they work?
- Plasticizers are substances that are injected into polymeric materials to provide or improve the elasticity or plasticity required for reprocessing or use. They facilitate free-flowing material dispersion.
- Is polyvinyl chloride a base plasticizer?
- If the polymer is soluble in the plasticizer, it is called a base plasticizer. Polyvinyl chloride (PVC) is the second pure polymer after polyethylene in the European market. Although polymer as a pure resin has poor applications and requires the use of additives to produce products of acceptable quality.
- Why did Farabi petrochemical switch from DOP to DOTP?
- In other case for the first time, Farabi Petrochemical in order adaptation to modern science, switched one of the producing line of DOP to DOTP in 20,000 t/y capacity. The following points were obtained by reviewing the information of FIPCO company:
