Biological Effects of the Plasticizer Tris (2-Ethylhexyl
The effects of these plasticizers on human leukemia (HL)-60 viability and breast cancer cell MCF-7 proliferations were investigated. Furthermore, the affinity of these plasticizers for binding human estrogen receptor (ER)-α was measured using an enzyme-linked immunosorbent assay (ELISA) kit.
Biological Effects of the Plasticizer Tris (2-Ethylhexyl
The effects of these plasticizers on human leukemia (HL)-60 viability and breast cancer cell MCF-7 proliferations were investigated. Furthermore, the affinity of these plasticizers for binding...
iop Clinical Pharmacology Biopharmaceutics
Objectives: An alternative plasticizer, tris (2-ethylhexyl) trimellitate (TOTM), was developed from di-(2-ethylhexyl) phthalate (DEHP) for use in medical tubing. However, little is known about the biological effects of TOTM and thus its safety is not yet well-established.
Comparison of tris(2-ethylhexyl) phosphate and di(2
Tris(2-ethylhexyl) phosphate (TEHP, CAS no. 78-42-2) is a plasticizer and a flame retardant, while di(2-ethylhexyl) phosphoric acid (DEHPA, CAS no. 298-07-7) is an oil additive and extraction solvent. Publicly-available information on repeated exposure to these two related organophosphate compounds is fragmentary.
Metabolites of 4-methylbenzylidene camphor (4-MBC
Metabolites of 4-methylbenzylidene camphor (4-MBC), butylated hydroxytoluene (BHT), and tris (2-ethylhexyl) trimellitate (TOTM) in urine of children and adolescents in Germany - human biomonitoring results of the German Environmental Survey GerES V (2014-2017) Environ Res. 2025 Jan;192:110345. doi: 10.1016/j.envres.2025.110345. Epub 2025 Oct 20.
- Is tris 2 ethylhexyl trimellitate safe?
- Objectives: An alternative plasticizer, tris (2-ethylhexyl) trimellitate (TOTM), was developed from di- (2-ethylhexyl) phthalate (DEHP) for use in medical tubing. However, little is known about the biological effects of TOTM and thus its safety is not yet well-established.
- Does plasticizer Di 2 ethylhexyl phthalate (DEHP) cause endocrine disruption?
- Electronic address: richard.leask@mcgill.ca. The ubiquitous presence of the plasticizer di (2-ethylhexyl) phthalate (DEHP) in the environment is of concern due to negative biological effects associated with it and its metabolites. In particular, the metabolite mono (2-ethylhexyl) phthalate (MEHP) is a potential endocrine disruptor.
- What is tri- (2-ethylhexyl) trimellitate?
- Tri- (2-ethylhexyl) trimellitate (TOTM or TEHTM) is a plasticizer for PVC material and is increasingly in demand (Van Vliet et al. 2011; SCENIHR 2015).
- What is tehtm plasticizer?
- Tri- (2-ethylhexyl) trimellitate (TEHTM) is a plasticizer for polyvinyl chloride (PVC) material used in medical devices. It is an alternative to di- (2-ethylhexyl) phthalate (DEHP), a well-known reprotoxic and endocrine disruptor. As plasticizers are known to easily migrate when in contact with fatty …
- Do plasticizers affect human leukemia viability and breast cancer cell MCF-7 proliferation?
- The effects of these plasticizers on human leukemia (HL)-60 viability and breast cancer cell MCF-7 proliferations were investigated. Furthermore, the affinity of these plasticizers for binding human estrogen receptor (ER)-α was measured using an enzyme-linked immunosorbent assay (ELISA) kit.
- What is a diester 1 DI-2 ethylhexyl trimellitate?
- The diester 1,2-di- (2-ethylhexyl) trimellitate (1,2-DEHTM) and the monoester 2-MEHTM were synthesized by the Institute for Thin Film and Microsensoric Technology e.V. (Teltow, Germany) with a stated chemical purity of at least 95% each.
