Characterization of phthalate plasticizers by HPLC
Characterization of phthalate plasticizers by HPLC/thermospray mass spectrometry. Author links open overlay panel John K. Baker. Show more. Add to Mendeley. Share. Cite.
Characterization of phthalate plasticizers by HPLC
Characterization of phthalate plasticizers by HPLC/thermospray mass spectrometry - ScienceDirect Journal of Pharmaceutical and Biomedical Analysis Volume 15, Issue 1, October 1996, Pages 145-148 Short communication Characterization of phthalate plasticizers by HPLC/thermospray mass spectrometry John K. Baker Add to Mendeley
Characterization of phthalate plasticizers by HPLC
Characterization of phthalate plasticizers by HPLC/thermospray mass spectrometry J Pharm Biomed Anal. 1996 Oct;15(1):145-8.doi: 10.1016/0731-7085(96)01830-4. Author J K Baker 1 Affiliation 1Alcon Laboratories, Inc., Fort Worth, TX 76134-2099, USA. PMID: 9011223 DOI:
Machine learning-assisted non-destructive plasticizer
phthalate plasticizers that have been primarily used in combination with DEHP and DINP16. DBP is a suspected endocrine disruptor, so its usage is regulated and restricted for use in toys in the
Analysis of Phthalates and Alternative Plasticizers in Gloves
The purpose of the present study was to develop two orthogonal methods, GC-MS and HPLC-DAD, for the screening of plasticizers in gloves. Performances of these two methods were compared in terms of ease of use, number of analyzed plasticizers, and sample preparation.
- What is a phthalate elution?
- An isocratic elution was performed using methanol–water (75/25 %) as a mobile phase. Standard calibration curves were linear for all three analytes. Phthalates are the most widely used plasticizers in plastic industry.1 Phthalates are dialkyl or alkyl aryl esters of 1, 2-benzene dicarboxylic acid.
- How was phthalate derivatives analyzed?
- HPLC instrument was used for analysis of these phthalate derivatives. A reversed phase isocratic and gradient elution and UV detection method was used for the individual and simultaneous determination of these phthalate derivatives. HPLC was carried out using a C18 column and spectrophotometric detection at 230nm.
- Does dimethyl phthalate elute faster than diethyl and dibutyl phthalates?
- As per the chromatogram obtained during the analysis of the phthalate derivatives confirms that dimethyl phthalate with low retention time elutes faster than diethyl and dibutyl phthalates. In future studies, I recommend performing the analysis for these phthalate derivatives by using 5μ
- Is phthalate a hazard?
- Since phthalate exposure is considered to potentially have adverse effects on human health, analytical methodology for measuring their migration into food and beverages has been extensively reported.1 Also, diethyl phthalate (DEP) and dibutyl phthalate (DBP) are used in personal care products, lacquers, varnished and coatings.
- How are plasticizers separated from Phenomenex?
- Separation of plasticizers was performed on a C8 column (Kinetex 100 mm × 4.6 mm; 2.6 μm) from Phenomenex (La Pecq, France) preceded by a guard cartridge (2 mm × 4.6 mm; same stationary phase), and maintained at 35 °C. The mobile phase was a mixture of water and ACN.
- What is HPLC used for?
- HPLC is routinely used for both qualitative and quantitative analysis of environmental, pharmaceutical, industrial, forensic, clinical, and consumer product sample. Because, a fixed volume sample loop provides a more precise and accurate injection, quantitative HPLC is easier than other analysis.
