Dermal bioaccessibility of plasticizers in indoor dust and clothing
Dermal bioaccessibility of phthalates and alternative plasticizers The transdermal exposure of chemicals from dust or clothing into the human body is a two-step process including releasing from the matrix and penetrating across the skin.
Dermal bioaccessibility of plasticizers in indoor dust and clothing
Dermal bioaccessibility of plasticizers in indoor dust and clothing Dermal bioaccessibility of plasticizers in indoor dust and clothing Sci Total Environ. 2025 Jul 1;672:798-805. doi: 10.1016/j.scitotenv.2025.04.028. Epub 2025 Apr 3. Authors
Dermal bioaccessibility of plasticizers in indoor dust and clothing
An in vitro physiologically based extraction test was employed to investigate the dermal bioaccessibility of target phthalates and alternative plasticizers from indoor dust and clothing. Temperature, incubation time, sweat/sebum ratio and solid/liquid ratio were selected to study their effects on the bioaccessibility.
Dermal bioaccessibility and absorption of polycyclic aromatic
The dermal bioavailability of PAHs in indoor dust was estimated by multiplying the bioaccessibility of PAHs in indoor dust by the ratio of dermal absorption by skin cells, and ranged from 0.12 to 51.0%. These data will be useful in risk assessments. Graphical abstract Download : Download high-res image (251KB) Download : Download full-size image
Dermal bioaccessibility of plasticizers in indoor dust and clothing
Regarding plasticizers from indoor dust and clothing, the bio accessibility of Diethyl phthalates (DEP), dibutyl phthalate (DBP), bis-2-ethylhexyl phthalate (DEHP), Acetyl tributyl citrate...
- Do plasticizers affect dermal bioaccessibility?
- For indoor dust, when the K OW was below 7.45, there was obvious linear association between the dermal bioaccessibility of plasticizers and their corresponding K OW (Fig. S1, Table S4).
- Are Paes & APS bioaccessible from indoor dust and clothing?
- An in vitro physiologically based extraction test was employed to investigate the dermal bioaccessibility of target PAEs and APs from indoor dust and clothing. Temperature, incubation time, sweat/sebum ratio and solid/liquid ratio were selected to study their effects on the bioaccessibility.
- Do phthalates and alternative plasticizers release in indoor dust and clothing?
- However, the release of phthalates and alternative plasticizers in indoor dust and clothing has been poorly studied. Therefore, indoor dust and clothing were chosen to be estimate the dermal bioaccessibility of typical phthalates and alternative plasticizers to perform a more accurate risk assessment.
- Does temperature affect dermal bioaccessibility of Paes and APS?
- Temperature, incubation time, sweat/sebum ratio and solid/liquid ratio were selected to study their effects on the bioaccessibility. The dermal bioaccessibility of PAEs and APs achieved maximum levels at 36.3 °C, except for ATBC and DEHA at 40 °C in indoor dust.
- How does Kow affect dermal bioaccessibility of plasticizers?
- For T-shirt and jeans, when the K OW was below 4.90, the dermal bioaccessibility of plasticizers was increased according to the increase of K OW, and then showed declining trend with the increase of K OW (>4.90).
- What is dermal bioaccessibility?
- Dermal bioaccessibility could be defined as “the fraction of the total amount of contaminants contained in an environmental matrix that is released into fluids of skin surface and available for dermal absorption ( Pawar et al., 2017 ).”
