Diisobutyl phthalate
Diisobutyl phthalate ( DIBP) is a phthalate ester having the structural formula C6H4(COOCH2CH (CH3)2)2. It is formed by the esterification of isobutanol and phthalic anhydride. This and other phthalates are used as plasticizers due to their flexibility and durability.
Risk Evaluation for Di-isobutyl Phthalate - (1,2-Benzene
Di-isobutyl phthalate (CASRN 84-69-5) is a colorless liquid. The primary use for di-isobutyl phthalate is a plasticizer in adhesive and sealant manufacturing. Information from the 2016 Chemical Data Reporting (CDR) for di-isobutyl phthalate indicates the reported production volume is less than 1,000,000 lbs/year (manufacture and import).
Distribution, source apportionment, and health risk
Di (2-ethylhexyl) phthalate (DEHP), di-iso-butyl phthalate (DIBP), and di-n-butyl phthalate (DBP) were the dominant compounds of Σ 8 PAEs in indoor dusts from residences and dormitories. The administrative levels revealed that the highly serious contamination occurred in the provincial capital, followed by nonprovincial cities and countries.
ISO 8124-6:2018 - Safety of toys — Part 6: Certain phthalate
This document specifies a method for the determination of di-iso-butyl phthalate (DIBP), di-n-butyl phthalate (DBP), benzylbutyl phthalate (BBP), bis- (2-ethylhexyl) phthalate (DEHP), di-n-octyl phthalate (DNOP), di-iso-nonylphthalate (DINP) and di-iso-decyl phthalate (DIDP) (as specified in Annex A) in toys and children's products.
Biomarkers of phthalates and alternative plasticizers in the
Biomarkers of phthalates and alternative plasticizers in the Flemish Environment and Health Study (FLEHS IV): Time trends and exposure assessment Biomarkers of phthalates and alternative plasticizers in the Flemish Environment and Health Study (FLEHS IV): Time trends and exposure assessment Epub 2025 Feb 11. Authors
- What is Diisobutyl phthalate (DIBP)?
- Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ?
- ) Diisobutyl phthalate (DIBP) is a phthalate ester having the structural formula C6H4(COOCH2CH (CH3)2)2. It is formed by the esterification of isobutanol and phthalic anhydride.
- How is dibutyl phthalate excreted?
- When it comes to excretion, DIBP is first converted into the hydrolytic monoester monoisobutyl phthalate (MIBP). The primary excretory route is urine, with biliary excretion being noted in minor amounts. DIBP has lower density and freezing point than the related compound dibutyl phthalate (DBP).
- What is the s2cid for Diisobutyl phthalate?
- ISSN 2211-7156. S2CID 240582041. ^ "Metabocard for Diisobutyl phthalate". The Human Metabolome Database (HMDB).
- What is the metabolite of DIBP?
- The main metabolite of DiBP is mono-isobutyl phthalate (MiBP), which makes up 70% of the excretion products. MiBP can be oxidized to either 2OH-mono-isobutyl phthalate (2OH-MiBP) or 3OH-mono-isobutyl phthalate (3OH-MiBP), which make up 20% and 1% of the excretion products respectively.
- How is DIBP synthesized?
- DIBP is synthesized by reaction of phthalic anhydride with isobutanol. Various acids are used as a catalyst, such as sulfuric acid, sulfonated graphene, or iron (III) chloride. Water is a byproduct. Using sulfuric acid, the yield is 61% yield.
- Does Diisobutyl phthalate impair androgen-dependent reproductive development?
- Toxicological Sciences. 125 (2): 544–557. doi: 10.1093/toxsci/kfr315. PMC 3262859. PMID 22112501. ^ Saillenfait AM, Sabaté JP, Gallissot F (October 2008). "Diisobutyl phthalate impairs the androgen-dependent reproductive development of the male rat". Reproductive Toxicology. 26 (2): 107–115.
