Guideline on the use of phthalates as excipients in human
Dibutyl phthalate (DBP) DBP was associated with an anti-androgenic effect in a human cell line as it inhibited the binding of dihydrotestosterone to the androgen receptor with an IC 50 of 74 M (Christen et al. 2010). DBP was devoid of oestrogenic activity in vitro (Lee et al. 2012).
Dibutyl phthalate
Dibutyl phthalate (DBP) is an organic compound which is commonly used as a plasticizer because of its low toxicity and wide liquid range. With the chemical formula C 6 H 4 (CO 2 C 4 H 9 ) 2 , it is a colorless oil, although commercial samples are often yellow.
Guidance for Industry - Food and Drug Administration
exposure to dibutyl phthalate (DBP) and di(2-ethylhexyl) phthalate (DEHP). In particular, the guidance recommends that you, as part of the pharmaceutical industry, avoid the use of these two
Dibutyl phthalate 99 84-74-2 - Sigma-Aldrich
Dibutyl phthalate (DBP) is most commonly used as a plasticizer in a variety of household products. It has the ability to leach and evaporate into the environment while using or disposing of these products. [ 1] [ 2] Therefore, studies are being conducted to assess its toxic and apoptotic effects. [ 1]
Risk Evaluation for Dibutyl Phthalate (1,2-Benzene
Dibutyl phthalate (CASRN 84-74-2) is a colorless to faint yellow oily liquid. The primary use for dibutyl phthalate is as a plasticizer, in adhesives and sealants, and paints and coatings.
