Dibutyl phthalate 99 84-74-2 - Sigma-Aldrich
Dibutyl phthalate (DBP) is most commonly used as a plasticizer in a variety of household products. It has the ability to leach and evaporate into the environment while using or disposing of these products. [ 1] [ 2] Therefore, studies are being conducted to assess its toxic and apoptotic effects. [ 1]
Dibutyl phthalate
Dibutyl phthalate ( DBP) is an organic compound which is commonly used as a plasticizer because of its low toxicity and wide liquid range. With the chemical formula C 6 H 4 (CO 2 C 4 H 9) 2, it is a colorless oil, although commercial samples are often yellow. [3] Production and use [ edit]
Guideline on the use of phthalates as excipients in human medicinal
Dibutyl phthalate (DBP) DBP was associated with an anti-androgenic effect in a human cell line as it inhibited the binding of dihydrotestosterone to the androgen receptor with an IC 50 of 74 M (Christen et al. 2010). DBP was devoid of oestrogenic activity in vitro (Lee et al. 2012).
Guidance for Industry - Food and Drug Administration
exposure to dibutyl phthalate (DBP) and di(2-ethylhexyl) phthalate (DEHP). In particular, the guidance recommends that you, as part of the pharmaceutical industry, avoid the use of these two
Phthalate Di-butyl phthalate - GreenFacts
Di-butyl phthalate. Context - Dibutyl Phthalate (DBP) is used in a wide range of products for everyday use such as plastics, paints, inks and cosmetics. Its widespread use has raised some concerns on the safety of this compound. Is DBP posing a risk to health or the environment? The same information on.
