Diisononyl Phthalate (DINP) Reference List - US EPA

                                               
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Manufacturer-Requested Risk Evaluation of Diisononyl

                                               
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Substance Information - ECHA - Europa

                                               
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Phthalates - ECHA - Europa

                                               
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Diisononyl phthalate - DINP - Sigma-Aldrich

                                               
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  • What are Di-isononyl phthalate esters (dinps)?
  • Di-isononyl phthalate esters (DINPs) are endocrine-disrupting chemicals and have replaced di (2-ethylhexyl) phthalate (DEHP) as the major plasticizer for poly (vinyl chloride) (PVC) products in recent years. Exposure marker discovery of DINPs is crucial, because of their high potential for human exposure and toxicity.
  • What is diisononyl phthalate (DINP)?
  • Diisononyl phthalate (DINP) has been widely used in polyvinyl chloride (PVC) products and is ubiquitous as a substitute; however, its toxicity due to exposure remains to be determined.
  • What is DINP phthalic acid (Diisodecyl phthalate)?
  • DINP is typically a mixture of chemical compounds consisting of various isononyl esters of phthalic acid, and is commonly used in a large variety of plastic products. The European Union has set a maximum specific migration limit (SML) from food contact materials of 9 mg/kg food for the sum of diisononyl phthalates and diisodecyl phthalates.
  • How did EPA evaluate diisononyl phthalate (DINP)?
  • EPA gathered and evaluated physical and chemical property data and information according to the process described in the Systematic Review Protocol for Diisononyl Phthalate (DINP) (U.S. EPA, 2025b).
  • Is diisononyl phthalate (DINP) carcinogenic?
  • Diisononyl phthalate (DINP) carcinogenicity hazard assessment. Submitted to California Office of Environmental Health Hazard Assessment. Report. HERO ID: 2079253. 296. Fan, Y.L., et al. (2018).
  • What is diisononyl phthalate?
  • Diisononyl phthalate is the diisononyl ester of benzene-1,2-dicarboxylic acid. It has a role as a plasticiser. It is a phthalate ester and a diester. See also: Diisononyl phthalate (DINP) (annotation moved to) ... View More ... Conformer generation is disallowed since too flexible bis (7-methyloctyl) benzene-1,2-dicarboxylate