Effect of Plasticizer Type on Tensile Property and In Vitro
This study developed the interests of low-methoxyl pectin (LMP) together with plasticizers for the preparation of elastic thin films. The effect of different plasticizer types (glycerol: Gly; sorbitol: Sor; propylene glycol: PG; and polyethylene glycol 300: PEG 300) and concentrations (2040% w/w
Effect of Plasticizer Type on Tensile Property and In Vitro
The effect of different plasticizer types (glycerol: Gly; sorbitol: Sor; propylene glycol: PG; and polyethylene glycol 300: PEG 300) and concentrations (20–40% w/w) on mechanical and thermal properties of LMP films as well as on in vitro release of indomethacin were evaluated.
Effect of Plasticizer Type on Tensile Property and In Vitro
LMP Gly-plasticized and PG-plasticized films containing indomethacin as a model drug were prepared and the influence of plasticizers on tensile, thermal properties and indomethacin release was investigated. There was no significant difference in in vitro indomethacin release between non-plasticized, Gly-plasticized and PG-plasticized LMP films.
Effect of Plasticizer Type on Tensile Property and In Vitro
Effect of Plasticizer Type on Tensile Property and In Vitro Indomethacin Release of Thin Films Based on Low-Methoxyl Pectin. Sign in | Create an
Effect of plasticizer type on tensile property and in vitro
Addition of plasticizers from 20% to 40% caused reduction in the tensile strength and Young's modulus values, whereas percent elongation was increased. Forty percent Gly-plasticized and PG-plasticized films were selected to deliver indomethacin in comparison with non-plasticized film.
- How do plasticizer contents affect film tensile strength?
- The films' moisture contents were increased when increasing the plasticizer contents. The tensile strengths were decreased, but elongations at break were increased; 7.38%–11.54% for G-plasticized films, 10.17%–15.76% for S-plasticized films, and 14.41%– 16.10% for SG-plasticized films with increasing plasticizer concentrations of the film samples.
- Does plasticizer affect tensile strength of SPS films?
- The effect of different plasticizer types and concentrations on the tensile strength of SPS films is shown in Figure 1. The presence of plasticizer at lower concentration of 15% demonstrated high tensile strength value of 28.35 MPa for S-plasticized films, 15.82 MPa for GS-plasticized films and 9.59 MPa for G-plasticized films.
- Do plasticizers affect tensile strength?
- The different plasticizers utilized in the film-forming solution have remarkable effects on the tensile, thermal and barrier properties of the resulting films. In all the plasticized SPS films, the tensile strength decreased with plasticizer content from 15%–45%.
- Does plasticizer concentration affect thermal properties of s-plasticized films?
- Change in plasticizer concentration showed an insignificant effect on the thermal properties of S-plasticized films. The glass transition temperature of SPS films slightly decreased as the plasticizer concentration increased from 15% to 45%.
- Why do SG-plasticized films have a low tensile strength?
- This was because SG-plasticized film was a mixture of plasticizers for sorbitol and glycerol. Consequently, the resultant films (SG-plasticized films) enhanced G-plasticized films' low tensile strength and impaired the higher S-plasticized films' tensile strength.
- Does plasticizer type and concentration affect biodegradable films?
- Generally, the current study verified that plasticizer type and concentration affects the mechanical, thermal and barrier properties of plasticized SPS films. In summary, this paper presents a potential biopolymer for the development of biodegradable films.
