Effect of polymer, plasticizer and filler on orally
Incorporation of plasticizer (PEG 400 and glycerin) reduced tensile strength but increased elasticity of the ODF formed. PVP increased both tensile strength and elasticity of the ODF. Increase in MCC:mannitol ratio reduced the tensile strength and elasticity of the ODF.
Effect of polymer, plasticizer and filler on orally
Incorporation of plasticizer (PEG 400 and glycerin) reduced tensile strength but increased elasticity of the ODF formed. PVP increased both tensile strength and elasticity of the ODF. Increase in MCC:mannitol ratio reduced the tensile strength and elasticity of the ODF.
Sci-Hub | Effect of polymer, plasticizer and filler on orally
Liew, K. B., Tan, Y. T. F., & Peh, K.-K. (2013). Effect of polymer, plasticizer and filler on orally disintegrating film. Drug Development and Industrial Pharmacy, 40
Effect of polymer, plasticizer and filler on orally
Context: Difficulty in swallowing tablets or capsules has been identified as one of the contributing factors to non-compliance of geriatric patients. Although orally disintegrating tablet was designed for fast disintegration in mouth, the fear of taking solid tablets and the risk of choking for certain patient populations still exist.Objective: The objective of this study was to develop and
Effect of polymer, plasticizer and filler on orally
Effect of polymer, plasticizer and filler on orally disintegrating film. Sign in | Create an account. https://orcid.org. Europe PMC. Menu. About. About Europe PMC
- What is screening optimization and characterization of polymers for oral dissolving films?
- Screening Optimization and Characterization of Polymers for Orally Dissolving Films (ODFs) is an important process in the development of novel drug delivery systems. ODFs are thin films that can dissolve in the mouth, allowing for rapid drug absorption through the oral mucosa.
- Can polymers be used in oral fast dissolving film?
- Therefore their use is limited in oral fast dissolving film. To make them useful, it was one of the attempts to combine them with semi-synthetic or synthetic polymers and to check resultant properties of film for their acceptability. Films were prepared from aqueous dispersions of polymers.
- Can natural polymers influence ODF properties?
- In this review, we analyzed ODFs developed using natural polymers or blends involving natural polymers, such as maltodextrin, pullulan, starch, gelatin, collagen, alginate, chitosan, pectin, and others, to overview the recent publications and discuss how natural polymers can influence ODFs properties. 1. Introduction
- Can biopolymers be used in the production of orally disintegrating films?
- Conclusion Different biopolymers can be used in the production of orally disintegrating films, since they have film-forming capacity. Their production is based on different techniques like casting, tape casting and extrusion, or more recently by the printing techniques.
- Does glycerin increase tensile strength and elasticity of ODF?
- Incorporation of plasticizer (PEG 400 and glycerin) reduced tensile strength but increased elasticity of the ODF formed. PVP increased both tensile strength and elasticity of the ODF. Increase in MCC:mannitol ratio reduced the tensile strength and elasticity of the ODF.
- Is glycerol a good plasticizer for pullulan films?
- Vuddanda et al. studied the effect of plasticizers with various physicochemical properties, such as glycerol, vitamin E TPGS, and triacetin in pullulan ODFs, concluding that glycerol in a concentration of 20–30% (w /w) is an excellent plasticizer to achieve acceptable physicochemical properties of pullulan films for ODF application.
