Effects of plasticizers and their mixtures on estrogen receptor and
Plasticizers are additives used to increase the flexibility or plasticity of the material to which they are added, normally rigid plastic and as additives in paint and adhesives. They are suspected to interfere with the endocrine system, including the estrogen and the thyroid hormone (TH) systems.
Effects of plasticizers and their mixtures on estrogen receptor and
Any disruption of ER signaling pathways can contribute to adverse health effects such as infertility, declining human sperm count and quality, developmental abnormalities and endocrine related cancers ( McLachlan et al., 2006, Sikka and Wang, 2008 ).
Effects of plasticizers and their mixtures on estrogen receptor and
Any disruption of ER signaling pathways can contribute to adverse health effects such as infertility, declining human sperm count and quality, developmental abnormalities and endocrine related cancers (McLachlan et al., 2006, Sikka and Wang, 2008).
Effects of plasticizers and their mixtures on estrogen receptor and
Table of contents – Volume 189, Issue 1 . Show all volumes and issues. The tables of contents are generated automatically and are based on the data records of the individual con
Effects of plasticizers and their mixtures on estrogen receptor and
Plasticizers are additives used to increase the flexibility or plasticity of the material to which they are added, normally rigid plastic and as additives in paint and adhesives. They are suspected to interfere with the endocrine system, including the estrogen and the thyroid hormone (TH) systems. We investigated in vitro the thyroid hormone-like and estrogenic activities of a range of widely
- Do plastic products release estrogenic chemicals?
- Yang, C. Z.; Yaniger, S. I.; Jordan, V. C.; Klein, D. J.; Bittner, G. D. Most plastic products release estrogenic chemicals: A potential health problem that can be solved. Environ. Health Perspect. 2011, 119 (7), 989– 996, DOI: 10.1289/ehp.1003220
- Can rodent studies help us understand the toxic effects of plasticizers?
- Studies performed in rodents or using rodent- or human-derived tissues have been critical for understanding the toxic effects of plasticizers on the ovary and their mechanisms of action.
- Do plasticizers disrupt ovarian follicle populations?
- Exposure to plasticizers has been linked to shifts in ovarian follicle populations, indicating disruption of folliculogenesis ( Table 1 ).
