Phthalates - ECHA - Europa
Phthalates Phthalates form a family of synthetic chemicals with a wide variety of uses, ranging from consumer to industrial products. There are different kind of phthalates and they are commonly used as softeners to make plastics, such as PVC, more flexible and durable.
FOUR CLASSIFIED PHTHALATES (DEHP, BBP, DBP AND DIBP) - Europa
use of certain articles containing four classified phthalates (DEHP, BBP, DBP and DIBP). These phthalates are primarily found in PVC as softeners but they can also be found in low concentrations in other plastics and in e.g. dispersions, paints and varnishes. These phthalates are all reported to affect reproductivity. The widespread use of these
EFSA: Updated risk assessment of five phthalates
The assessment found that current exposure to these phthalates from food is not of concern for public health. For DBP, BBP, DEHP, and DINP, exposure was found to range from 7 g/kg bw to a maximum of 12 g/kg bw (between seven and four times below the set TDI). For DIDP, dietary exposure was found to be 1,500 times below the set TDI.
Risk Management for Phthalates | US EPA
Eight chemicals are included in the Phthalates Action Plan (PDF): dibutyl phthalate (DBP), diisobutyl phthalate (DIBP), butyl benzyl phthalate (BBP), di-n-pentyl phthalate (DnPP), di (2-ethylhexyl) phthalate (DEHP), di-n-octyl phthalate (DnOP), diisononyl phthalate (DINP), and diisodecyl phthalate (DIDP). Why is EPA concerned?
ANNEX XV RESTRICTION REPORT PROPOSAL FOR A RESTRICTION - Europa
SUBSTANCE NAMES: FOUR PHTHALATES (DEHP, BBP, DBP, DIBP) IUPAC NAMES: Bis(2-ethylhexyl) phthalate Benzyl butyl phthalate Dibutyl phthalate Bis(2-methylpropyl) benzene-1,2-dicarboxylate EC NUMBER(S): 204-211-0, 201-622-7, 201-557-4, 201-553-2 CAS NUMBER(S): 117-81-7, 85-68-7, 84-74-2, 84-69-5 CONTACT DETAILS OF THE DOSSIER SUBMITTER:
- Does DIBP affect risk assessment of phthalates?
- Given its high potency relative to DEHP as the index substance, inclusion of DIBP can make a major impact on the outcome of an exposure assessment to a group of phthalates and on the risk characterisation – see for example Appendix C – Considerations on DIBP. Risk assessment of phthalates for use in FCM
- Is a comprehensive review of DBP phthalates possible?
- Due to the limited time for completion of the opinion and the large amount of new evidence available since the 2005 publication of the EFSA AFC Panel’s assessments of DBP, BBP, DEHP, DINP and DIDP (EFSA, 2005a,b,c,d,e), the Panel considered it unfeasible to perform a comprehensive review of all the new data on these phthalates.
- How many phthalates are in a dossier?
- The Dossier Submitter presents the four phthalates as a group of substances on the basis of their common physicochemical properties, common anti-androgenic mode of action, and similar use. The spectrum of effects in the male rat associated with exposure to the four phthalates is known in literature as the phthalate syndrome.
- Which phthalates can not be placed on the market after 7 July 2020?
- According to this restriction,10DEHP, DBP, BBP and DIBP shall not be placed on the market after 7 July 2020 in articles, individually or in any combination of these phthalates, in a concentration equal to or greater than 0.1% by weight of the plasticised material in the article (but with some exemptions).
- Are phthalates banned in Denmark?
- Denmark prepared a report proposing a restriction on the placing on the market and use of certain articles containing four classified phthalates (DEHP, BBP, DBP and DIBP). These phthalates are primarily found in PVC as softeners but they can also be found in low concentrations in other plastics and in e.g. dispersions, paints and varnishes.
- Is DBP a critical step in the reproductive toxicity of phthalates?
- www.efsa.europa.eu/efsajournal 54 EFSA Journal 2019;17(12):5838 during a window of susceptibility in rats, induced by DBP, BBP and DEHP, as a critical step in the reproductive toxicity of the phthalates.
