Substance Information - ECHA - Europa
Harmonised classification and labelling (CLH) Harmonised classification and labelling is a legally binding classification and labelling for a substance, agreed at European Community level. Harmonisation is based on the substance’s physical, toxicological and eco-toxicological hazard assessment.
Glossary: Dibutyl phthalate (DBP) - European Commission
DBP, also known as DNBP, is a phthalate with the same core structure as DIDP and DINP but with two shorter side chains attached, each having four carbon atoms. In the 1990s, over 75% of DBP was used as plasticiser in plastics such as PVC, 14% in adhesives, 7% in printing inks
Guideline on the use of phthalates as excipients in human
Dibutyl phthalate (DBP) DBP was associated with an anti-androgenic effect in a human cell line as it inhibited the binding of dihydrotestosterone to the androgen receptor with an IC 50 of 74 M (Christen et al. 2010). DBP was devoid of oestrogenic activity in vitro (Lee et al. 2012).
Substance Name: Dibutyl phthalate (DBP) CAS Number: 84-74-2
dibutyl phthalate; DBP 201-557-4 84-74-2 Repr. 1B Aquatic Acute 1 H360Df H400 GHS08 GHS09 Dgr H360Df H400 Classification and labelling of DBP according to Annex VI, Table 3.2 of Regulation (EC) No 1272/2008 (The list of harmonized classification and labelling of hazardous substances from Annex I to Directive 67/548/EEC) Index No International
1 June 2009 Background document for dibutyl phthalate (DBP)
DBP is a specialist plasticiser often used in combination with other high molecular weight phthalates. It is also used as a gelling aid in combination with other plasticizers for nitrocellulose, cellulose ether, and polyacrylate and polyacetate dispersions.
- What is a glass forming dibutyl phthalate (DBP)?
- In the following example, the glass forming dibutyl phthalate (DBP), with a glass temperature Tg =178 K, was investigated by NFS (sensitive to translational and rotational dynamics) and SRPAC (sensitive only to rotational dynamics) (Sergueev et al., 2003). Ferrocene was used as probe molecules.
- Are phthalates the same as DBP?
- Otake et al. (2004) concluded that the concentration of phthalates is 100 – 1000 times higher in indoor air compared to outdoor air. They also found a significant correlation between DBP and DEHP. This suggested that these two phthalates have the same emission profiles or come from the same products.
- What is DBP absorption?
- Chemical/Pharmaceutical/Other Class: Steroid hormones DBP absorption. Only indirect methods are available for determination of the structure, the best known of which is DBP absorption. In this method, dibutyl phthalate (DBP) is added drop by drop to a certain amount of carbon black, placed in a calibrated kneading machine.
- What is DBP metabolite?
- Therefore, DBP has become ubiquitous in the environment, and can now be found in food, water, and air. The major metabolite for DBP is monobutyl phthalate (MBP). However, this metabolite is also considered one of the major metabolites for another phthalate, benzyl butyl phthalate (Ema, 1995).
- What does DBP stand for?
- NTP CERHR Monograph on the Potential Human Reproductive and Developmental Effects of Di n Butyl Phthalate (DBP). National Toxicology Program (NTP). (1995). Dibutyl Phthalate Feed Studies. Otake, T., Yoshinaga, J., & Yanagisawa, Y. (2004). Exposure to phthalate esters from indoor environment.
- Where does dibutyl phthalate come from?
- The largest source of exposure to dibutyl phthalate is from food, possibly fish and seafood; levels in fish ranged from 78 to 200 parts per billion (ppb). (1) ) were detected in the air near New York City. Dibutyl phthalate levels in rooms recently covered with polyvinyl chloride tiles ranged from 15,000 to 26,000 ng/m 3. (1)
