Nail Care Products | FDA - U.S. Food and Drug Administration
Dibutyl phthalate (DBP) has been used most commonly in nail polishes and some other products, such as nail hardeners, while dimethyl phthalate (DMP) and diethyl phthalate (DEP) are used occasionally.
Guidance for Industry - Food and Drug Administration
exposure to dibutyl phthalate (DBP) and di(2-ethylhexyl) phthalate (DEHP). In particular, the guidance recommends that you, as part of the pharmaceutical industry, avoid the use of these two
Risk Evaluation for Dibutyl Phthalate (1,2-Benzene
Dibutyl phthalate (CASRN 84-74-2) is a colorless to faint yellow oily liquid. The primary use for dibutyl phthalate is as a plasticizer, in adhesives and sealants, and paints and coatings.
Guideline on the use of phthalates as excipients in human
Dibutyl phthalate (DBP) DBP was associated with an anti-androgenic effect in a human cell line as it inhibited the binding of dihydrotestosterone to the androgen receptor with an IC 50 of 74 M (Christen et al. 2010). DBP was devoid of oestrogenic activity in vitro (Lee et al. 2012).
Phthalates: Uses, Safety Concerns, How to Read Labels
Phthalates are used in soft plastic teethers and baby toys and can be hazardous to a baby’s health. Additionally, babies crawl around, touch many things, and put their hands in their mouths. 8. The Centers for Disease Control and Prevention (CDC) notes that phthalate particles are present in dust.
- Is dibutyl phthalate toxic?
- Dibutyl phthalate (DBP) is most commonly used as a plasticizer in a variety of household products. It has the ability to leach and evaporate into the environment while using or disposing of these products. Therefore, studies are being conducted to assess its toxic and apoptotic effects.
- What is di-n-butyl phthalate used for?
- Di-n-butyl phthalate (DBP) is a commonly used plasticizer. It is also used as an additive to adhesives and printing inks. DBP is soluble in various organic solvents, such as alcohol, ether, and benzene. It is also used as an ectoparasiticide.
- What is dibutyl phthalate (DBP)?
- DBP is a phthalate with the same core structure as DIDP and DINP but with two shorter side chains attached, each having four carbon atoms. It is also referred to as '1,2-benzenedicarboxylic acid, dibutyl ester (9CI)'
- What is Diisobutyl phthalate?
- 1.039 g/mL at 25 °C (lit.) n 20/D 1.49 (lit.) clear liquid Diisobutyl Phthalate is a Dialkyl phthalate ester phthalate plasticizer which can be used as a substitute of dibutyl phthalate. Diisobutyl Phthalate as well as other phthalates have genotoxic effects and studies shown an increase in its monoester metabolite in human urine over the years.
- Is DIBP a type of phthalate?
- DIBP is a phthalate and is used as an additive to keep plastics soft or more flexible (plasticiser). It is often used in combination with other phthalates. DIBP is used in various applications such as nitro cellulose plastic, nail polish, explosive material, and lacquer manufacturing.
- Does dibutyl phthalate (DBP) selectively elimination of tumor cells from bone marrow?
- A new pharmacological activity of dibutyl phthalate (dbp) on selectiveelimination of tumor cells from bone marrow. Leukemia Research 17(7): 557-560.
