Review of Exposure and Toxicity Data for Phthalate Substitutes
The five chemicals identified by this report as the most likely o-DAP alternatives are acetyl tri-n-butyl citrate (ATBC), di(2-ethylhexyl) adipate (DEHA), 1,2- cyclohexanedicarboxylic acid, dinonyl ester (DINCH), trioctyltrimellitate (TOTM),and di(2-ethylhexyl) terephthalate (DEHT or DOTP).
DINP plasticizer | ExxonMobil Product Solutions
Jayflex DINP plasticizer is the largest-volume general-purpose high-molecular-weight plasticizer for PVC , providing the opportunity for cost savings with a good balance of properties. As shown below, it is an excellent substitute for Di (2-ethylhexyl) phthalate (DOP) in most flexible PVC applications.
Plasticizers used in food-contact materials affect
Notably, DiNP and DiDP are comprised in the EFSA list of permitted compounds and are indeed among the most used in the plastic market (33% United States; 63% European Union) as substitutes of di(2-ethylhexyl) phthalate (DEHP), a substance classified as SVHC [9, 10].
Phthalates and their Alternatives | CHEManager
Common alternatives include Hexamoll DINCH (DINCH), acetyl tributyl citrate (ATBC), dioctyl terephthalate (DOTP), 2,2,4-trimethyl 1,3-pentanediol diisobutyrate (TXIB), trioctyl trimellitate (TOTM) and di- (2-ethylhexyl) adipate (DEHA).
Exposure to phthalates DEHP and DINP May lead to oxidative
The current study addressed the issue regarding potential health consequences of DEHP and its industrial substitute DINP exposure in the kidney at doses that are currently deemed as safe. We have not only shown that at NOAEL doses, both DEHP and DINP could cause renal oxidative stress, but also demonstrated an overall disruption by both
