PHARMACEUTICALLY USED PLASTICIZERS: A REVIEW
example of good compatibility due to similar chemical structure (polarity, shape, size) is the oldest known plasticizer- polymer system: camphor and cellulose
PHARMACEUTICALLY USED PLASTICIZERS: A REVIEW - ResearchGate
The concentration of plasticizer affects the strength of coating films, overall integrity of drug products and drug release characteristics in therapeutic pharmaceutical dosage forms. 1, 2 The...
[PDF] Pharmaceutically Used Plasticizers | Semantic Scholar
The extensive use of polymers in medical and pharmaceutical applications including particularly packaging, medical devices, drug carriers and coatings has caused a substantial demand for the proper plasticizers. Although there are many plasticizers used in the chemical industry, only a few of them have been approved for pharmaceutical applications.
Pharmaceutically Used Plasticizers - IntechOpen
Recent Advances in Plasticizers 46 2. Pharmaceutically used plasticizers The primary role of all plasticizers as low molecular weight non-volatile additives is to improve the flexibility and processability of polymers by lowering the second order transition temperature (glass transition temperature, Tg) (Rosen, 1993). The extent of Tg
Pharmaceutical Plasticizers for Drug Delivery Systems
The concentration of plasticizer affects the strength of coating films, overall integrity of drug products and drug release characteristics in therapeutic pharmaceutical dosage forms. 1, 2 The...
- Are plasticizers a low molecular weight non-volatile additive?
- The primary role of all plasticizers as low molecular weight non-volatile additives is to improve the flexibility and processability of polymers by lowering the second order transition temperature (glass transition temperature, Tg) (Rosen, 1993).
- Are plasticizers suitable for pharmaceutical applications?
- The extensive use of polymers in medical and pharmaceutical applications including particularly packaging, medical devices, drug carriers and coatings has caused a substantial demand for the proper plasticizers. Although there are many plasticizers used in the chemical industry, only a few of them have been approved for pharmaceutical applications.
- Are natural-based plasticizers suitable for pharmaceutical and medical applications?
- The natural-based plasticizers characterized by low toxicity and low migration are required nowadays not only for pharmaceutical and medical applications. In this respect, most of traditional plasticizers are not applicable in this area.
- What is a plasticizer in chemistry?
- ABSTRACT A plasticizer is a substance the addition of which to another material makes that material softer and more flexible. Most often plasticizers are materials which, when added to a polymer, cause an increase in the flexibility and workability, brought about by a decrease in the glass-transition temperature of the polymer.
- Which substances were used as plasticizers?
- Oily, waxy, or fatty substances were applied as plasticizers. Other invention relates to an oral pulse release comprising a polymer micromatrix, a first active ingredient distributed substantially uniformly within polymer micromatrix and a second active ingredient deposited on the surface of the polymer matrix (Gadre et al., 2006).
- Are polymeric drug delivery systems plasticizers?
- Plasticizer as minor component of polymeric drug delivery systems has not been strictly defined. Even liquid drugs or liquids with a potential pharmacodynamic effect can serve as plasticizers. As well structural water in the hydrophilic polymer seems to be an internal plasticizer of the polymeric drug delivery systems.
