Release Enhancement by Plasticizer Inclusion for Amorphous
Purpose Plasticizers are commonly used in the preparation of amorphous solid dispersions (ASDs) with the main goal of aiding processability; however, to the best of our knowledge, the impact of plasticizers on drug release has not been explored. The goal of this study was to evaluate diverse plasticizers, including glycerol and citrate derivatives, as additives to increase the drug loading
Release Enhancement by Plasticizer Inclusion for Amorphous
Purpose: Plasticizers are commonly used in the preparation of amorphous solid dispersions (ASDs) with the main goal of aiding processability; however, to the best of our knowledge, the impact of plasticizers on drug release has not been explored.
Plasticizer Enhancement on the Miscibility and
In previous research, a polylactic chitin starch composite was prepared without the use of a solvent to enhance the miscibility. In this study, a polylactic acid (PLA) chitin starch composite was produced with chloroform as a plasticizer in the ratio 1:10. The blending of chitin and starch with PLA
Plasticizer Enhancement on the Miscibility and
The water absorption test shows that the water absorption rate increases with starch content and the wear rate recorded sample A (92% P/8% C) as the highest. The high miscibility projected was...
Plasticizers: Types, Uses, Classification, Selection & Regulation
A primary plasticizer enhances elongation, softness and flexibility of polymer. They are highly compatible with polymers and can be added in large quantities. For example: up to 50% of vinyl gloves are made up of plasticizers, which make the PVC flexible and soft enough to wear.
- Does plasticizer enhance polylactic acid-chitin-starch composite properties?
- Plasticizer Enhancement on the Miscibility and Thermomechanical Properties of Polylactic Acid-Chitin-Starch Composites.
- What is a good plasticizer?
- Non volatile organic solvents or low molecular weight polymers are mostly used as plasticizer. For example, polyethylene glycol (PEG-200, PEG-400, PEG-600), dimethylforamide (DMF), ethylene carbonate (EC), propylene carbonate (PC) etc are reported as good plasticizers.
- Do Plasticizers improve tensile strength and elongation of PLA films?
- The mechanical properties of the PLA film were significantly improved by the plasticizers, with the tensile strength and elongation at break of PLA-7% GT increasing from 0.44 MPa to 1.32 % to 1.08 MPa and 12.53 %. Moreover, the presence of these plasticizers markedly increased the enzymatic degradation rate of PLA films.
- Does plasticizer increase crystallization rate in PLLA?
- The results indicated that incorporating 10 % of the polyester plasticizer into PLLA decreased its Tg to 56.3 °C and increased its elongation at break by approximately 50 %. Furthermore, the addition of 10 % plasticizer significantly enhanced the overall crystallization rate and the growth rate of spherical crystals in PLLA. 3.4. Cardanol
- Why do we add plasticizer?
- The addition of plasticizer leads to a decrease in intermolecular forces along polymer chains, which improves the flexibility and chain mobility. These are added to enhance film flexibility, decrease brittleness and avoid shrinking during handling and storage , , .
- What are plasticizers used for?
- Plasticizers are an important class of low molecular weight non-volatile compounds that are widely used in polymer industries as additives . The primary role of such substances is to improve the flexibility and processability of polymers by lowering the second order transition temperature, the glass transition temperature (Tg).
