Non-phthalate plasticizer DEHT preserves adequate blood
Our study demonstrates that the plasticizer DEHT provides adequate blood component quality. We propose DEHT as a strong future candidate for replacement of DEHP in blood bags. Non-phthalate plasticizer DEHT preserves adequate blood component quality during storage in PVC blood bags Vox Sang. 2025 Jan;116(1):60-70.doi: 10.1111/vox.12982.
Analytical methods for the determination of DEHP plasticizer
It was also successfully used by Rothenbacher et al. [50] to determine if a rapid screening test for plasticizers (like DEHP, DINP, or DINCH) in PVC materials can be developed using direct analysis in real time mass spectrometry (DART-MS). An open interface would allow the direct insertion of solid specimens, such as samples of medical devices.
Leaching of the plasticizer di(2-ethylhexyl)phthalate (DEHP
Di(2-ethylhexyl)phthalate (DEHP) is a widely used plasticizer to render poly(vinyl chloride) (PVC) soft and malleable. Plasticized PVC is used in hospital equipment, food wrapping, and numerous other commercial and industrial products.
The DEHP/Plasticizer Test | Cyclingnews Forum
The 99.9% upper reference values of the control group were determined at 54.4 ng/mL for 5oxo-MEHP and 94.8 ng/mL for 5OHMEHP which are 12- and 9-fold lower than the lowest value measured after blood transfusion. Note in this study, the 5 patients gave two samples between 0 to 24 hours.
Full article: The contamination of DEHP on the surfaces
ABSTRACT. This study conducted laboratory tests and field surveys to understand the plasticizer contamination characteristics on the surface of PVC flooring materials used indoors, and discussed the risk of exposure of plasticizers to infants indoors. A lab experiment was conducted to measure the bleed-out of DEHP on PVC sheet surfaces.
- Why is DEHP used in plasticization and processing of PVC?
- The excellent performance of DEHP in the plasticization and processing of PVC explains its wide use in medical devices over the past few years. The strategy was to adjust the chemical nature of the lateral alkyl chains in order to reduce the leaching of the plasticizers into the surrounding medium.
- What happens if you eat plasticizer DEHP?
- Plasticizer DEHP ( Fasano, Bono-Blay, Cirillo, Montuori, & Lacorte, 2012) is a toxic plastic softener widely used in chemical industry that can make the distribution of particles more uniform and increase the ductility, elasticity and softness. However, if DEHP is eaten by human, it may affect the liver and kidney, and even cause cancer.
- How to identify alternative plasticizers?
- It is easy to obtain general information using very simple non-separative methods suitable for identifying the alternative plasticizers. These methods rely on the general features of polymers, like PVC and their plasticizers, such as thermolability and spectral and electromagnetic characteristics.
- Which plasticizers are used in MDS?
- The review focuses on the aternative to DEHP plasticizers currently used in the MDs. Their migration from PVC depends partially on their physicochemical properties. The patient׳s exposure is the main risk and has to be investigated. Appropriate analytical methods are developed to quantify them in different matrices.
- Which plasticizer is the most stable?
- TOTM appears to be the most stable plasticizer in short-term and long-term thermal stability studies (Fig. 2) . Fig. 2. Weight loss of traditional plasticizers (including TOTM) and ionic liquids during long-term stability of 20 wt% plasticized samples at 100 °C (from Rahman et al. ).
- What is diethylhexylphthalate (DEHP)?
- Until 2010, diethylhexylphthalate (DEHP) was the plasticizer most commonly used to soften PVC medical devices (MDs), because of a good efficiency/cost ratio. In flexible plasticized PVC, phthalates are not chemically bound to PVC and they are released into the environment and thus may come into contact with patients.
