Phthalates: Are They Safe? - WebMD

                                               
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Diethylhexyl phthalate - GreenFacts

                                               
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5 Most important facts about Dioctyl phthalate (DOP) - Ideh

                                               
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Bis(2-ethylhexyl) phthalate

                                               
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The Facts about DEHP/DOP - Spina Dental

                                               
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  • What is DEHP/DOP used for?
  • It is a broad-spectrum plasticizer used mostly to render polyvinyl chloride products soft, pliable, and durable. DEHP/DOP is the most widely used plasticizer in the manufacture of many vinyl products, including disposable gloves. Q: Why is there increased interest in DEHP/DOP?
  • How safe is DINP compared to DEHP (DOP)?
  • Compared with DEHP, DINP has almost no effect on the reproduction or development of experimental animals. In summary, DINP is relatively safer than DEHP (DOP), but it is only an industrial plasticizer and does not fall into the category of safe food additives.
  • How much do you know about DEHP in medical devices?
  • This article discusses the extensively used phthalate DEHP, with global production estimated to be between 1 and 4 million tonnes in 1994 (Kl6pffer 1994 cited in Huber* et al, 1996).
  • What is the LOAEL of DEHP?
  • The oral LOAEL for adults exposed to DEHP is 425 mg/kg bw/d (Lamb et al., 1987). Humans have 2-3 fold lower levels of intestinal lipases than rats.
  • How reliable is DEHP data?
  • Reliable, relevant and adequate measured data for emissions is only available for a limited number of sites using DEHP (representing less than 5% of the total DEHP use).
  • What is the daily volume of DEHP intake?
  • The worst-case scenario for inhalation exposure to DEHP involves breathing air saturated with DEHP continuously for 24 hours/day. With a vapour pressure of 4.8x10-4Pa at 37°C (4.8 x 10-9 atm) and a mean flow rate of 10 L/min, the daily volume of DEHP intake would be 6.9 x 10-5 L/day. (Health Canada, 2002)