DEHP phthalates in medical devices - GOV.UK
Safe use of medical devices with DEHP Phthalates are chemicals added to polyvinyl chloride ( PVC) plastic to make it softer and more flexible. Di (2-ethylhexyl) phthalate ( DEHP) is the type...
Diethylhexyl phthalate - GreenFacts
DEHP is a chemical form of dioctyl phthalate or DOP DEHP has the same core structure as DBP, DIDP and DINP, but has longer, branched side chains attached, each having 8 carbon atoms. DEHP is a colourless oily liquid. It is soluble in fat and not very soluble in water. The same information on Level 1: Summary Level 2: Details Level 3: Source 2.
6. Does DEHP pose risks to human health? - GreenFacts
There is concern for the testicular effects, fertility, toxicity to kidneys, on repeated exposure and developmental toxicity for workers as a consequence of inhalation and dermal exposure during production, processing and industrial end-use of preparations or materials containing DEHP. There is no concern for the acute toxicity, irritation and
Bis(2-ethylhexyl) phthalate
Due to its suitable properties and the low cost, DEHP is widely used as a plasticizer in manufacturing of articles made of PVC. [8] Plastics may contain 1% to 40% of DEHP. It is also used as a hydraulic fluid and as a dielectric fluid in capacitors. DEHP also finds use as a solvent in glowsticks .
Di(2-Ethylhexyl)Phthalate (DEHP) | ToxFAQs | ATSDR
DEHP is found throughout the environment at low levels. It gets into the environment mostly through the disposal of plastic waste in landfills. Most DEHP in the environment is found in sediments and soil. It sticks strongly to soil and breaks down slowly when it is near the surface. Indoors, DEHP can also stick to dust particles.
- What is DEHP/DOP used for?
- It is a broad-spectrum plasticizer used mostly to render polyvinyl chloride products soft, pliable, and durable. DEHP/DOP is the most widely used plasticizer in the manufacture of many vinyl products, including disposable gloves. Q: Why is there increased interest in DEHP/DOP?
- Is DEHP carcinogenic to humans?
- IARC has concluded that DEHP is possibly carcinogenic to humans (Group 2B). In 1988, JECFA evaluated DEHP and recommended that human exposure to this compound in food be reduced to the lowest level attainable. JECFA considered that this might be achieved by using alternative plasticizers or alternatives to plastic material containing DEHP.
- Is DEHP still necessary in medical devices?
- The Medical Device Regulations (SI 2002 No 618, as amended) (UK MDR 2002) require any materials presenting a hazard to be replaced as soon as alternatives with a more positive risk-to-benefit balance are available. It seems that DEHP may still be essential in some medical devices in critical circumstances.
- What are the Occupational Standards for DEHP?
- Occupational standards for DEHP WEL = workplace exposure limit. LTEL = long-term exposure limit. STEL = short-term exposure limit. Health and Safety Executive (HSE). ‘EH40/2005 Workplace Exposure Limits . Fourth Edition’ 2020. (viewed on 117 January 2025) Table 7. Public health standards and guidelines World Health Organisation.
- Is Deha present in drinking water?
- Reports of the presence of DEHA in surface water and drinking-water are scarce, but DEHA has occasionally been identified in drinking-water at levels of a few micrograms per litre. As a consequence of its use in PVC films, food is the most important source of human exposure (up to 20 mg/day).
